4 Results for "

A2058 cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "A2058 cells" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-16462
CAS No.: 1263369-28-3
Target:  

CDK

Research Areas:  

Cancer

CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8), has an IC50 of 5 nM and 7 nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively.
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Cat. No.: HY-N7085
CAS No.: 487-06-9
Synonyms: 5,7-Dimethoxycoumarin; Limettin
Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through heat shock protein-70, monoamine oxidase-A and inhibition of apoptosis .
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Cat. No.: HY-N7085R
CAS No.: 487-06-9
Synonyms: 5,7-Dimethoxycoumarin (Standard); Limettin (Standard)
Citropten (Standard) is the analytical standard of Citropten. This product is intended for research and analytical applications. Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through heat shock protein-70, monoamine oxidase-A and inhibition of apoptosis .
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Cat. No.: HY-174837
Target:  

Topoisomerase

Research Areas:  

Cancer

Topoisomerase IIα-IN-11 (Compound 16h) is a potent Topoisomerase IIα inhibitor. Topoisomerase IIα-IN-11 shows significant inhibition on melanoma A2058 cell lines (IC50 3-6 μM). Topoisomerase IIα-IN-11 is promising for research of cancers (especially melanoma) .
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