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28 Results for "

ACAT-1

" in MedChemExpress (MCE) Product Catalog:

Products (28)

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Avasimibe

20 Publications Verification

Cat. No.: HY-13215

CAS No.: 166518-60-1

Purity: 99.77%

Synonyms: CI-1011; PD-148515

Target:

Acyltransferase

Research Areas:

Cancer

Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC₅₀s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively ^[1]. Avasimibe can be used for the research of prostate cancer .

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K-604 dihydrochloride

7 Cited Publications

Cat. No.: HY-100400A

CAS No.: 217094-32-1

Purity: 99.42%

Target:

Acyltransferase

Research Areas:

Cardiovascular Disease

K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC₅₀ of 0.45±0.06 μM.

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Nevanimibe

5 Cited Publications

Cat. No.: HY-100399

CAS No.: 133825-80-6

Synonyms: PD-132301; ATR-101

Target:

Acyltransferase Apoptosis

Research Areas:

Cancer

Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC₅₀ of 9 nM. Nevanimibe inhibits ACAT2 with an EC₅₀ of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer ^[1].

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Nevanimibe hydrochloride

5 Cited Publications

Cat. No.: HY-100399A

CAS No.: 133825-81-7

Purity: 99.49%

Synonyms: PD-132301 hydrochloride; ATR101 hydrochloride

Target:

Acyltransferase Apoptosis

Research Areas:

Cancer

Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC₅₀ of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC₅₀ of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer ^[1].

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ACAT1 Protein, Human (His)

1 Cited Publications

Cat. No.: HY-P78986

Purity: ≥ 90%, as determined by reducing SDS-PAGE.

Synonyms: ACAT1; Acetyl-Coenzyme A Acetyltransferase 1; Prev. ACAT; MAT; Acetyl-CoA Acetyltransferase, Mitochondrial; T2; Acetoacetyl-CoA Thiolase; Mitochondrial Acetoacetyl-CoA Thiolase; THIL; Testicular Tissue Protein Li 198; Acetyl-CoA Acetyltransferase 1; Aceto

Species:

Human

Source:

E. coli

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