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21 Results for "

ACAT-2

" in MedChemExpress (MCE) Product Catalog:

Products (21)

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Avasimibe

20 Publications Verification

Cat. No.: HY-13215

CAS No.: 166518-60-1

Purity: 99.77%

Synonyms: CI-1011; PD-148515

Target:

Acyltransferase

Research Areas:

Cancer

Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC₅₀s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe can be used for the research of prostate cancer ^[2].

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Nevanimibe

5 Cited Publications

Cat. No.: HY-100399

CAS No.: 133825-80-6

Synonyms: PD-132301; ATR-101

Target:

Acyltransferase Apoptosis

Research Areas:

Cancer

Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC₅₀ of 9 nM. Nevanimibe inhibits ACAT2 with an EC₅₀ of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer .

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Nevanimibe hydrochloride

5 Cited Publications

Cat. No.: HY-100399A

CAS No.: 133825-81-7

Purity: 99.49%

Synonyms: PD-132301 hydrochloride; ATR101 hydrochloride

Target:

Acyltransferase Apoptosis

Research Areas:

Cancer

Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC₅₀ of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC₅₀ of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer .

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Pyripyropene A

1 Cited Publications

Cat. No.: HY-117832

CAS No.: 147444-03-9

Purity: 99.71%

Category:

Cardiovascular Disease Microorganisms Terpenoids Sesquiterpenes Disease Research Fields Inflammation/Immunology

Target:

Acyltransferase

Pyripyropene A is an orally active, potent and selective sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) inhibitor, with an IC₅₀ of 0.07 µM. Pyripyropene A attenuates hypercholesterolemia and atherosclerosis in vivo ^[2] .

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