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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
ACK1/TNK2
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "ACK1/TNK2" in MCE Product Catalog:
Target:
Ack1 JAK Anaplastic lymphoma kinase (ALK) Src Bcr-Abl Checkpoint Kinase (Chk) FGFR ROS Kinase
Research Areas:
(R)-9b is an ATP-competitive kinase inhibitor. (R)-9b binds to the ATP-binding site of ACK1/TNK2, inhibiting their kinase activity and autophosphorylation, with a human IC50 of 56 nM. (R)-9b also inhibits JAK2, Tyk2, ALK, c-Src, ABL1, CHK1, FGFR1, LCK, and ROS/ROS1. (R)-9b can be used for research on prostate cancer [1].
Cat. No.: HY-E70868
Thirty-eight-negative kinase-1 (TNK1) is a member of the ACK family of NRTKs, which includes only two human kinases, TNK1 and TNK2 (also called ACK1). TNK1 Recombinant Human Active Protein Kinase is a recombinant TNK1 protein that can be used to study TNK1-related functions [1].
Cat. No.: HY-P75542
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TNK2; ACK; Tyrosine Kinase Non Receptor 2; Activated Cdc42-Associated Kinase 1; ACK1; ACK-1; Tyrosine Kinase Non-Receptor Protein 2; Non-Specific Protein-Tyrosine Kinase; Activated CDC42 Kinase 1; Tyrosine Kinase, Non-Receptor, 2; P21cdc42Hs; Activated P2
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
