Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
670 Results for "
AChE Inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (670)
670 Results for "AChE Inhibitor" in MCE Product Catalog:
27
27 Publications Verification
Synonyms: E2020 free base
Target:
Research Areas:
Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively .
27
Target:
Research Areas:
Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE . Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity .
16
Category:
Target:
16
Category:
Target:
13
13 Cited Publications
Research Areas:
α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 µM) and acetylcholinesterase (AChE; IC50=300 µM). α-NETA has anti-cancer activity .
8
8 Cited Publications
Cat. No.: HY-B2244
CAS No.: 206658-92-6
Target:
Research Areas:
Tacrine hydrochloride (hydrate) is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.
8
Target:
Research Areas:
Tacrine hydrochloride is a potent brain-penetrant inhibitor of both AChE and BChE, with IC50s of 31 nM and 25.6 nM, respectively. Tacrine hydrochloride is also a NMDAR inhibitor, with an IC50 of 26 μM. Tacrine hydrochloride can be used for the research of Alzheimer’s disease .
8
Target:
Research Areas:
Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease .
6
6 Cited Publications
Cat. No.: HY-N0826
CAS No.: 18797-79-0
Corynoline is an orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM. Corynoline exhibits multiple activities including anti-inflammatory, antinociceptive, antitumor and analgesic effects. Corynoline can be used in the research of diseases such as tumors and inflammatory pain .
6
6 Cited Publications
Research Areas:
MAPK-IN-1 (Compound 2) is a MAPK signaling pathway inhibitor. MAPK-IN-1 exhibits AChE inhibitory activity with an IC50 of 23.84 μM. MAPK-IN-1 shows anti-neuroinflammatory and neuroprotective activity and can be used for Alzheimer's disease research .
6
Category:
Alkaloids Plant Neurological Disease Anti-aging Terpenoids Huperziaceae Extract Huperzia serrata (Thunb. ex Murray) Trevis. Extract Sesquiterpenes Pyridine Alkaloids Disease Research Fields
Target:
5
5 Cited Publications
Synonyms: Gelseminic acid; Chrysatropic acid
Category:
Leguminosae/Fabaceae Extract Hedyotis diffusa Willd. Extract Glycyrrhiza uralensis Fisch. Extract Coumarins Plant Monophenols Phenols Phenylpropanoids Disease Research Fields Inflammation/Immunology Rubiaceae Extract
Target:
5
5
5
5 Cited Publications
5
5 Cited Publications
Cat. No.: HY-N0226A
CAS No.: 889665-86-5
4
4
Category:
Rutaceae Extract Skimmia reevesiana Fort. Extract Alkaloids Plant Quinoline Alkaloids Disease Research Fields Inflammation/Immunology
Target:
3
3 Cited Publications
Cat. No.: HY-17541A
CAS No.: 2197053-49-7
Target:
Research Areas:
Cysteine Protease inhibitor hydrochloride, an inhibitor of Cysteine Protease, binds to acetylcholinesterase (AChE). Cysteine Protease inhibitor hydrochloride is applicable to the research of Alzheimer's disease .
3
3 Cited Publications
Cat. No.: HY-N6029
CAS No.: 111664-82-5
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
