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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
ALF
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "ALF" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone
Category:
Alkaloids Piperidine Alkaloids Plant Zygophyllaceae Extract Other Diseases Tribulus terrester Linn. Extract Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-N1131A
CAS No.: 33973-59-0
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
Target:
Research Areas:
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) hydrochloride is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .
1
1 Cited Publications
Cat. No.: HY-N1131B
CAS No.: 10581-38-1
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone monohydrate
Category:
Alkaloids Piperidine Alkaloids Plant Other Diseases Other Families Extract Disease Research Fields
Target:
Synonyms: L768242
Research Areas:
GW-405833 (L768242) is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. GW-405833 also exhibits non-competitive CB1 antagonist, exerting its analgesic and and anti-inflammatory effect through a CB1 receptor (rather than CB2) dependent mechanism. GW-405833 can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF) .
Cat. No.: HY-N1131S
CAS No.: 52168-48-6
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone-d17
Cat. No.: HY-P99138
Target:
Research Areas:
Synonyms: L768242 hydrochloride
Research Areas:
GW405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. GW405833 hydrochloride also exhibits non-competitive CB1 antagonist, exerting its analgesic effect through a CB1 receptor (rather than CB2) dependent mechanism. GW405833 hydrochloride can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 hydrochloride inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF) .
Cat. No.: HY-154802
CAS No.: 2307311-19-7
Research Areas:
TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
Cat. No.: HY-RS18890
Target:
Research Areas:
Afm Mouse Pre-designed siRNA Set A contains three designed siRNAs for Afm gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00433
Target:
Research Areas:
AFM Human Pre-designed siRNA Set A contains three designed siRNAs for AFM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-177809
Target:
Research Areas:
aptTNF-α sodium is a TNF-α-targeting aptamer that has tissue protective effect and systemic anti-inflammatory effect upon acute tissue injury using the mouse acute lung injury (ALI) and acute liver failure (ALF) models.
Cat. No.: HY-P70036B
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AFM; Alpha-Albumin; Afamin; Vitamin E Binding Protein; ALB2; Alpha-Alb; ALBA; ALF
Species:
Human
Source:
HEK293
Cat. No.: HY-P11486
Research Areas:
Cat. No.: HY-P11859
Research Areas:
Cat. No.: HY-110036AR
CAS No.: 1202865-22-2
Synonyms: L768242 hydrochloride (Standard)
Target:
Reference Standards Cannabinoid Receptor Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase TNF Receptor Interleukin Related
Research Areas:
GW405833 hydrochloride (Standard) is the analytical standard of GW405833 (hydrochloride) (HY-110036A). This product is intended for research and analytical applications. GW405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. GW405833 hydrochloride also exhibits non-competitive CB1 antagonist, exerting its analgesic effect through a CB1 receptor (rather than CB2) dependent mechanism. GW405833 hydrochloride can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 hydrochloride inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF) .
Cat. No.: HY-110036R
CAS No.: 180002-83-9
Synonyms: L768242 (Standard)
Target:
Reference Standards Cannabinoid Receptor Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase TNF Receptor Interleukin Related
Research Areas:
GW-405833 (Standard) is the analytical standard of GW-405833 (HY-110036). This product is intended for research and analytical applications. GW-405833 (L768242) is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. GW-405833 also exhibits non-competitive CB1 antagonist, exerting its analgesic and and anti-inflammatory effect through a CB1 receptor (rather than CB2) dependent mechanism. GW-405833 can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
