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21 Results for "

ANO1

" in MedChemExpress (MCE) Product Catalog:

Products (21)

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Emidurdar

6 Publications Verification

Cat. No.: HY-105917

CAS No.: 265646-85-3

Purity: 99.41%

Synonyms: Endovion; NS3728

Target:

Chloride Channel

Research Areas:

Others

Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor ^[1] .

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August 31

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T16Ainh-A01

3 Cited Publications

Cat. No.: HY-100612

CAS No.: 552309-42-9

Purity: ≥99.0%

Target:

Chloride Channel

Research Areas:

Others

T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC₅₀ value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) ^[1] .

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Ani9

2 Cited Publications

Cat. No.: HY-119981

CAS No.: 356102-14-2

Purity: 99.12%

Target:

Chloride Channel

Research Areas:

Neurological Disease Cancer

Ani9 is an ANO1 inhibitor, with an IC₅₀ of 77 nM. Ani9 can inhibit smooth muscle contractions in mice and is applicable in research related to diseases such as tumors ^[1] .

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ANO1-IN-1

2 Cited Publications

Cat. No.: HY-146320

CAS No.: 407587-01-3

Purity: 99.57%

Target:

Chloride Channel

Research Areas:

Cancer

ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC₅₀ of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells ^[1].

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