1 Result for "

APNO 5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "APNO 5" in MCE Product Catalog:

Cat. No.: HY-D3066
CAS No.: 2207602-75-1
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology

APNO-5 is a photoacoustic probe for in vivo nitric oxide (NO) detection. APNO-5 contains a PEGylated tetraalkylammonium group, which reduces aggregation and promotes tissue and cellular uptake. APNO-5 rapidly reacts with NO via N-nitrosation in the presence of O2 to generate the N-nitroso product tAPNO-5, causing a 91 nm blueshift in the maximum absorption wavelength (from 764 nm to 673 nm), thereby enabling ratiometric photoacoustic imaging at excitation wavelengths of 770 nm (APNO-5) and 680 nm (tAPNO-5). APNO-5 exhibits high selectivity for NO over other reactive nitrogen species, oxidants, and biological carbonyl species .
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