12 Results for "

APP/PS1

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "APP/PS1" in MCE Product Catalog:

2
gp91 ds-tat
gp91 ds-tat
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2 Cited Publications
Cat. No.: HY-P5381
CAS No.: 329902-61-6
Target:  

NADPH Oxidase Ferroptosis Reactive Oxygen Species (ROS) Glutathione Peroxidase TRP Channel

Research Areas:  

Cardiovascular Disease Neurological Disease Inflammation/Immunology

gp91 ds-tat, a biological active peptide, is a NADPH oxidase 2 (Nox2) inhibitor. gp91 ds-tat blocks NADPH oxidase-dependent superoxide production. gp91 ds-tat ameliorates high glucose-induced increase in total ROS, LPOs and iron levels. gp91 ds-tat inhibits homocysteine (Hcy)-induced activation of NLRP3 inflammasomes and restores Hcy-inhibited lysosomal TRPML1 channel activity. gp91 ds-tat improves cerebrovascular and cognitive function in APP/PS1 mice. gp91 ds-tat can be used for the study of Alzheimer’s disease (AD), glomerular inflammation and cardiovascular disease .
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2
Isolinderalactone
Isolinderalactone
0 Images
2 Cited Publications
Cat. No.: HY-N3001
CAS No.: 957-66-4
Category:  

Lauraceae Extract Terpenoids Sesquiterpenes Plants Disease Research Fields 500 - Internal Server Error | MedChemExpress

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