12 Results for "

ASC oligomerization

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "ASC oligomerization" in MCE Product Catalog:

11
NLRP3/AIM2-IN-3
NLRP3/AIM2-IN-3
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11 Publications Verification
Cat. No.: HY-144226
CAS No.: 1787787-60-3
Purity:  98.23%
Target:  

NOD-like Receptor (NLR) AIM2 Pyroptosis

Research Areas:  

Inflammation/Immunology

NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with differential species specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. NLRP3/AIM2-IN-3 shows inhibitory efficacy against pyroptosis in THP-1 macrophages stimulated with LPS/nigericin, with an IC50 of 0.077 ± 0.008 μM. NLRP3/AIM2-IN-3 disturbs the interaction of NLRP3 or AIM2 with the adaptor protein ASC and inhibited ASC oligomerization .
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5
ADS032
ADS032
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5 Cited Publications
Cat. No.: HY-156798
CAS No.: 2757333-37-0
Purity:  99.74%
Target:  

NOD-like Receptor (NLR) Interleukin Related

Research Areas:  

Inflammation/Immunology

ADS032 is a sulfonylurea compound that is an NLRP1 and NLRP3 inflammasome inhibitor. ADS032 reduces the secretion of inflammatory factors and inhibits the oligomerization of ASC. ADS032 has anti-inflammatory effects in a variety of inflammatory models and can be used in the study of inflammatory diseases .
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3
Tabersonine
Tabersonine
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3 Cited Publications
Cat. No.: HY-N1431
CAS No.: 4429-63-4
Category:  

Alkaloids Plants Indole Alkaloids Apocynaceae Extract 500 - Internal Server Error | MedChemExpress

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