763 Results for "

AchE

" in MedChemExpress (MCE) Product Catalog:
Products (763)

763 Results for "AchE" in MCE Product Catalog:

27
Donepezil
Donepezil
0 Images
27 Publications Verification
Cat. No.: HY-14566
CAS No.: 120014-06-4
Purity:  99.82%
Synonyms: E2020 free base
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease Cancer

Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively .
loading...
    loading...
View All Sizes
27
Donepezil Hydrochloride
Donepezil Hydrochloride
0 Images
27 Publications Verification
Cat. No.: HY-B0034
CAS No.: 120011-70-3
Synonyms: E2020
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease Cancer

Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE . Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity .
loading...
    loading...
View All Sizes
16
Galanthamine
Galanthamine
0 Images
16 Cited Publications
Cat. No.: HY-76299
CAS No.: 357-70-0
Synonyms: Galantamine
Category:  

Alkaloids Other Alkaloids Plants Other Families Extract

Target:  

Cholinesterase (ChE) Apoptosis

Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM.
loading...
    loading...
View All Sizes
16
Galanthamine hydrobromide
Galanthamine hydrobromide
0 Images
16 Cited Publications
Cat. No.: HY-A0009
CAS No.: 1953-04-4
Synonyms: Galantamine hydrobromide
Category:  

Alkaloids Other Alkaloids Amaryllidaceae Extract Plants

Target:  

Cholinesterase (ChE) nAChR

Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC50 of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α3β4, α4β2, α6β4 nicotinic receptors ( nAChRs). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) .
loading...
    loading...
View All Sizes
13
α-NETA
α-NETA
0 Images
13 Cited Publications
Cat. No.: HY-138097
CAS No.: 115066-04-1
Purity:  ≥98.0%
Target:  

Chemerin Receptor Aldehyde Dehydrogenase (ALDH) Cholinesterase (ChE) Apoptosis

Research Areas:  

Cancer

α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 µM) and acetylcholinesterase (AChE; IC50=300 µM). α-NETA has anti-cancer activity .
loading...
    loading...
View All Sizes
8
Tacrine hydrochloride hydrate
Tacrine hydrochloride hydrate
0 Images
8 Cited Publications
Cat. No.: HY-B2244
CAS No.: 206658-92-6
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Tacrine hydrochloride (hydrate) is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.
loading...
    loading...
View All Sizes
8
Tacrine hydrochloride
Tacrine hydrochloride
0 Images
8 Cited Publications
Cat. No.: HY-B1488
CAS No.: 1684-40-8
Target:  

Cholinesterase (ChE) iGluR

Research Areas:  

Neurological Disease

Tacrine hydrochloride is a potent brain-penetrant inhibitor of both AChE and BChE, with IC50s of 31 nM and 25.6 nM, respectively. Tacrine hydrochloride is also a NMDAR inhibitor, with an IC50 of 26 μM. Tacrine hydrochloride can be used for the research of Alzheimer’s disease .
loading...
    loading...
View All Sizes
8
Tacrine
Tacrine
0 Images
8 Cited Publications
Cat. No.: HY-111338
CAS No.: 321-64-2
Purity:  99.91%
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease .
loading...
    loading...
View All Sizes
6
Isoimperatorin
Isoimperatorin
0 Images
6 Cited Publications
Cat. No.: HY-N0286
CAS No.: 482-45-1
Category:  

Neurological Disease 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.