Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
ActRIIB
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "ActRIIB" in MCE Product Catalog:
5
Target:
Research Areas:
Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .
1
Target:
Research Areas:
Cat. No.: HY-P990733
CAS No.: 2769700-97-0
Synonyms: KER-012
Target:
Research Areas:
Cat. No.: HY-P99818
CAS No.: 1169766-01-1
Synonyms: ACE-031
Target:
Research Areas:
Cat. No.: HY-P99720A
CAS No.: 1373715-00-4
Synonyms: RAP-536
Target:
Research Areas:
Cat. No.: HY-RS00249
Target:
Research Areas:
Acvr2b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acvr2b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00248
Target:
Research Areas:
ACVR2B Human Pre-designed siRNA Set A contains three designed siRNAs for ACVR2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183504
CAS No.: 3039974-35-8
Target:
Research Areas:
ActRIIB-IN-3 is a ActRIIB inhibitor. ActRIIB-IN-3 inhibits the ActRIIB protein in the MSTN pathway and induces the reversal of skeletal muscle atrophy associated with cancer cachexia. ActRIIB-IN-3 is applicable for the research of cancer cachexia .
Cat. No.: HY-W1142089
CAS No.: 3039974-32-5
Target:
Research Areas:
ActRIIB-IN-2 is an ActRIIB inhibitor with an IC50 of 1.1 nM. ActRIIB-IN-2 can be used for the research of cancer cachexia .
Cat. No.: HY-W1142093
CAS No.: 3039974-41-6
Target:
Research Areas:
ActRIIB-IN-4 (Compound 10) is an ActRIIB inhibitor with an IC50 of 4.0 nM. ActRIIB-IN-4 enhances muscle grip strength in tumor cachexia mice .
Cat. No.: HY-183005
CAS No.: 3039974-31-4
Target:
Research Areas:
ActRIIB-IN-1, 7-azaindole compound is an orally active activin type II receptor B (ActRIIB) inhibitor with an IC50 of 1.8 nM. ActRIIB-IN-1 can alleviate weight loss, muscle atrophy and decreased muscle strength caused by tumor cachexia, as well as improve appetite. ActRIIB-IN-1 can be used for the research of cancer cachexia .
Cat. No.: HY-P703681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Rat
Source:
HEK293
Cat. No.: HY-P703526
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
Sf9 insect cells
Cat. No.: HY-P700557
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
P. pastoris
Cat. No.: HY-P704048
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
Sf9 insect cells
Cat. No.: HY-P77290
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P75536
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P7456
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
HEK293
Cat. No.: HY-P72813
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
HEK293
Cat. No.: HY-P75535
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ActRIIB; Activin Receptor Type-2B; HTX4
Species:
Mouse
Source:
HEK293
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
