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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1755 Results for "
Adrenergic Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (1755)
1755 Results for "Adrenergic Receptor" in MCE Product Catalog:
102
Target:
Research Areas:
Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
102
102 Publications Verification
Cat. No.: HY-108353A
CAS No.: 299-95-6
Target:
102
102 Publications Verification
Synonyms: Isoproterenol hydrochloride
Target:
80
80 Cited Publications
Synonyms: Levarterenol; L-Noradrenaline
80
80 Cited Publications
Synonyms: Levarterenol hydrochloride; L-Noradrenaline hydrochloride
80
80 Cited Publications
Synonyms: Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate
80
80 Cited Publications
Synonyms: Levarterenol tartrate; L-Noradrenaline tartrate
55
Target:
55
Category:
Cardiovascular Disease Alkaloids Natural Products Plant Neurological Disease Other Alkaloids Aconitum carmichaeli Debx. Extract Disease Research Fields Ranunculaceae Extract
Target:
52
52 Cited Publications
Synonyms: ICI-118551 hydrochloride
Target:
Research Areas:
Zenidolol (ICI-118551) hydrochloride is a highly selective β2 adrenergic receptor antagonist, with Kis of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.
52
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Zenidolol (ICI-118551) is a selective β2-adrenergic receptor antagonist with Ki values of Zenidolol for β2, β1 and β3 adrenergic receptors of 0.7, 49.5 and 611 nM, respectively. Zenidolol exerts antitumor effects via inducing apoptosis, inhibiting tumor sphere formation, and downregulating the HIF pathway by blocking β2-AR on tumor cells. Zenidolol exhibits a unique pulmonary vessel-specific vasodilatory effect in mouse models. Zenidolol can be used as an intraocular pressure-lowering agent in ophthalmic disease research .
38
38 Cited Publications
Synonyms: (R)-(-)-Phenylephrine hydrochloride; L-Phenylephrine hydrochloride
Category:
Cardiovascular Disease Endogenous metabolite Alkaloids Plant Monophenols Lippia thymoides Mart. & Schauer Extract Other Alkaloids Phenols Verbenaceae Extract Disease Research Fields Endocrinology
Target:
38
38 Cited Publications
Synonyms: (R)-(-)-Phenylephrine; L-Phenylephrine
Target:
Research Areas:
(R)-(-)-Phenylephrine is a selective α1-adrenoceptor agonist primarily used as a decongestant.
37
37 Cited Publications
Synonyms: (+)-Medetomidine; (S)-Medetomidine
Target:
Research Areas:
Dexmedetomidine ((+)-Medetomidine) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine exhibits anxiolysis, sedation, and modest analgesia effects .
37
37 Cited Publications
Cat. No.: HY-17034A
CAS No.: 145108-58-3
Synonyms: (+)-Medetomidine hydrochloride; (S)-Medetomidine hydrochloride
Target:
Dexmedetomidine hydrochloride ((+)-Medetomidine hydrochloride) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine hydrochloride shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine hydrochloride exhibits anxiolysis, sedation, and modest analgesia effects .
28
28 Cited Publications
Target:
Research Areas:
CL316243 free acid is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors. CL316243 free acid is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 free acid has the potential for the treatment obesity, diabetes and urge urinary incontinence .
28
28 Cited Publications
Target:
Research Areas:
CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors .CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate . CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence .
21
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Endocrinology Cancer
Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris .
20
20 Cited Publications
Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis .
19
Category:
Alkaloids Plant Other Families Extract Disease Research Fields Endocrinology Indole Alkaloids
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
