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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
And-1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "And-1" in MCE Product Catalog:
Target:
Research Areas:
And1-IN-1 is a potent And1 inhibitor with an IC50 of 2.08 μM. And1-IN-1 binds to the N-terminus of And-1 and induces a conformational change in And-1, which promotes the interaction of And-1 with E3 ligase CUL4B for ubiquitin-mediated degradation. And1-IN-1 suppresses the growth of a broad range of cancers and resensitizes platinum-resistant ovarian cancer cells to platinum agents. And1-IN-1 can be used for the studies of ovarian cancer and breast cancer [1].
Cat. No.: HY-162896
CAS No.: 3029132-46-2
Target:
Research Areas:
And1 degrader 1 is an acidic nucleoplasmic DNA-binding protein 1 (And1) molecular glue-like degrader. And1 degrader 1 binds to the WD40 domain of And1 in a 'V' conformation to induce And1 degradation via the ubiquitin-proteasome pathway. And1 degrader 1 exhibits antiproliferative activity via synthetic lethal interaction with a PARP1 inhibitor to inhibit proliferation of cancer cells. And1 degrader 1 can be used for the research of non-small cell lung cancer (NSCLC) [1].
Cat. No.: HY-RS15758
Target:
Research Areas:
WDHD1 Human Pre-designed siRNA Set A contains three designed siRNAs for WDHD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22919
Target:
Research Areas:
Wdhd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Wdhd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701614
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD Repeat And HMG-Box DNA Binding Protein 1; And-1; CHTF4; CTF4; WD Repeat And HMG-Box DNA-Binding Protein 1; Acidic Nucleoplasmic DNA-Binding Protein 1; And1; CTF4, Chromosome Transmission Fidelity Factor 4 Homolog (S. Cerevisiae); CTF4, Chromosom
Species:
Human
Source:
HEK293
Cat. No.: HY-P701615
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD Repeat And HMG-Box DNA Binding Protein 1; And-1; CHTF4; CTF4; WD Repeat And HMG-Box DNA-Binding Protein 1; Acidic Nucleoplasmic DNA-Binding Protein 1; And1; CTF4, Chromosome Transmission Fidelity Factor 4 Homolog (S. Cerevisiae); CTF4, Chromosom
Species:
Human
Source:
HEK293
Cat. No.: HY-P75937
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NETO1; Brain-Specific Transmembrane Protein Containing 2 CUB And 1 LDL-Receptor Class A Domains Protein 1; Neuropilin And Tolloid Like 1; Neuropilin (NRP) And Tolloid (TLL)-Like 1; BTCL1; Neuropilin And Tolloid-Like Protein 1; BCTL1
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
