2 Results for "

Antcin C

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Antcin C" in MCE Product Catalog:

Antcin C
Antcin C
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Cat. No.: HY-N14553
CAS No.: 163565-76-2
Category:  

Microorganisms Ketones, Aldehydes, Acids

Target:  

Drug Derivative

Antcin C is an ergostane-type triterpenoid. Antcin C can be found in Antrodia cinnamomea .
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Antcin A
Antcin A
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Cat. No.: HY-N9921
CAS No.: 163597-24-8
Category:  

Microorganisms Steroids

Target:  

Pyroptosis NOD-like Receptor (NLR) MDM-2/p53 Glucocorticoid Receptor MicroRNA Na+/K+ ATPase SARS-CoV

Antcin A is an orally active modulator of p53 and glucocorticoid receptor (GR), with an IC50 of 8.55 μM against human GR. Through transcriptional activation of p53, Antcin A induces miR-200c and inhibits ZEB1, regulates epithelial-mesenchymal transition markers, and suppresses cancer cell migration/invasion. Antcin A activates GR, inhibits Na +/K +-ATPase and NLRP3 inflammasome assembly, pyroptosis (pyroptosis) and pro-inflammatory cytokine release, reduces hepatic lipid deposition, improves liver function, and reverses metabolic changes induced by the SARS-CoV-2 spike protein. Antcin A can be used in research related to breast cancer, head and neck cancer, non-alcoholic fatty liver disease, and coronavirus disease 2019 (COVID-19) .
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