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71 Results for "

Anti-HBV

" in MedChemExpress (MCE) Product Catalog:

Products (71)

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Nicotinamide

99 Publications Verification

Cat. No.: HY-B0150

CAS No.: 98-92-0

Synonyms: Niacinamide; Nicotinic acid amide

Category:

Alkaloids Human Gut Microbiota Metabolites Microorganisms Neurological Disease Pyridine Alkaloids Endogenous metabolite Disease Research Fields Cancer

Target:

Environmental Pollutants Endogenous Metabolite Sirtuin HBV Organoid

Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC₅₀: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD₊, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity .

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OSS_128167

38 Cited Publications

Cat. No.: HY-107454

CAS No.: 887686-02-4

Purity: 98.63%

Target:

Sirtuin HBV

Research Areas:

Infection Metabolic Disease Inflammation/Immunology Cancer

OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC₅₀s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects .

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RO8191

29 Cited Publications

Cat. No.: HY-W063968

CAS No.: 691868-88-9

Synonyms: CDM-3008; RO4948191

Target:

IFNAR JAK STAT HCV HBV

Research Areas:

Infection

RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC₅₀ of 200 nM for HCV replicon . RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti-HBV activity .

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