16 Results for "

Anti-aggregation

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "Anti-aggregation" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0375
CAS No.: 1449-05-4
18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis .
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1 Cited Publications
Cat. No.: HY-118752
CAS No.: 18046-21-4
Purity:  99.87%
Target:  

COX

Research Areas:  

Inflammation/Immunology

Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis .
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Cat. No.: HY-175552
Target:  

Tau Protein

Research Areas:  

Neurological Disease

CHIPOpt, a peptide, is an orthosteric CHIP TPR domain inhibitor with a Kd of ∼16 nM. CHIPOpt has anti-aggregation activity and decreases p.tau ubiquitination with little effect on unmodified tau. CHIPOpt can be used for Alzheimer’s disease research .
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Cat. No.: HY-N6661
CAS No.: 1196-01-6
Synonyms: (-)-Verbenone
Verbenone is a naturally derived monoterpene ketone and an anti-aggregation pheromone/attractant inhibitor. Verbenone interferes with the responses of Dendroctonus brevicomis and Dendroctonus ponderosae to baited traps. Verbenone can be used in studies related to bark beetle infestations of trees .
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Cat. No.: HY-N12360
CAS No.: 25166-14-7
2,3-Dehydrosilybin A is a pro-longevity and anti-aggregation compound .
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Cat. No.: HY-N0375R
CAS No.: 1449-05-4
18α-Glycyrrhetinic acid (Standard) is the analytical standard of 18α-Glycyrrhetinic acid. This product is intended for research and analytical applications. 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis .
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Cat. No.: HY-17482
CAS No.: 51484-40-3
Synonyms: Z-876
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Difenpiramide (Z-876) is a bisphenylalcanoic derivative with marked anti-inflammatory, analgesic, antipyretic and uricosuric properties. Difenpiramide has platelet anti-aggregation activity .
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Cat. No.: HY-19255
CAS No.: 227951-89-5
Research Areas:  

Others

FK-788 is a PGI(2) and IP agonist with a strong anti-aggregation effect, with an IC50 of 18 nM and a high binding affinity for the human recombinant IP receptor, with a Ki value of 20 nM .
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Cat. No.: HY-N12360R
CAS No.: 25166-14-7
2,3-Dehydrosilybin A (Standard) is the analytical standard of 2,3-Dehydrosilybin A. This product is intended for research and analytical applications. 2,3-Dehydrosilybin A is a pro-longevity and anti-aggregation compound .
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Cat. No.: HY-N6661R
CAS No.: 1196-01-6
Synonyms: (-)-Verbenone (Standard)
Verbenone (Standard) is the analytical standard of Verbenone. This product is intended for research and analytical applications. Verbenone ((-)-Verbenone) is a natural terpene in leaves of the tree, Verbena officinalis . Verbenone has anti-aggregation pheromone and interrupts the attraction of bark beetles to their aggregation pheromones .
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Cat. No.: HY-118752R
CAS No.: 18046-21-4
Target:  

COX Reference Standards

Research Areas:  

Inflammation/Immunology

Fentiazac (Standard) is the analytical standard of Fentiazac. This product is intended for research and analytical applications. Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis .
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Cat. No.: HY-146314
CAS No.: 2416910-88-6
Purity:  99.70%
Research Areas:  

Neurological Disease

MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects . MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-182304
CAS No.: 1338489-62-5
CLR01 sodium is a blood-brain barrier-permeable anti-aggregation agent. CLR01 sodium inhibits the de novo aggregation of Amyloid-β 40/42, α-synuclein, IAPP, tau protein and SOD1. CLR01 sodium reduces amyloid plaque burden in the cortex of triple-transgenic mice and improves the memory and motor abilities of these mice. CLR01 sodium can be used in research related to Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) .
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Cat. No.: HY-180346
CAS No.: 64134-31-2
Target:  

Huntingtin

Research Areas:  

Neurological Disease

Hepta-histidine is an inhibitor of Ku70-Huntingtin protein interaction. Hepta-histidine can reverse the morphological abnormalities of primary neurons differentiatied from hiPSCs. Hepta-histidine prolongs the lifespan in severe Huntington’s disease R6/2 mouse model. Hepta-histidine ameliorates DNA damage in vitro. Hepta-histidine can be used to study anti-aggregation agent against Tau-associated neurodegenerative diseases such as Alzheimer’s disease and Huntington’s disease .
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Cat. No.: HY-184817
CAS No.: 2883627-63-0
α-Synuclein-IN-22 is an α-Synuclein inhibitor with an IC50 of 2.7 μM against human α-Syn. α-Synuclein-IN-22 exerts anti-aggregation effects by stabilizing the native conformation of α-Syn, inhibiting the formation of β-sheet aggregates and inclusion bodies, and dissociating mature fibrils into functional monomers. α-Synuclein-IN-22 scavenges ROS and shows low cytotoxicity. α-Synuclein-IN-22 can be used in research related to Parkinson's disease .
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Cat. No.: HY-184815
CAS No.: 2883627-67-4
Research Areas:  

Neurological Disease

α-Synuclein-IN-20 is an inhibitor of α-synuclein (α-Synuclein) with an IC50 of 4.1 μM against human α-Syn. α-Synuclein-IN-20 exerts anti-aggregation effects by stabilizing the native conformation of α-Syn, inhibiting the formation of β-sheet aggregates and inclusion bodies, and dissociating mature fibrils into functional monomers. α-Synuclein-IN-20 scavenges ROS, protects and repairs dopaminergic neurons, ameliorates Parkinson's disease-like symptoms, and shows low cytotoxicity. α-Synuclein-IN-20 can be used for research related to Parkinson's disease .
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