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35 Results for "

Anti-leukemia

" in MedChemExpress (MCE) Product Catalog:

Products (35)

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6-Thioguanine

16 Publications Verification

Cat. No.: HY-13765

CAS No.: 154-42-7

Purity: 99.90%

Synonyms: Thioguanine; 2-Amino-6-purinethiol

Category:

Infection Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology Cancer

Target:

SARS-CoV Deubiquitinase DNA Methyltransferase Autophagy Apoptosis Endogenous Metabolite

6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC₅₀s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.

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VTP50469

13 Cited Publications

Cat. No.: HY-114162

CAS No.: 2169916-18-9

Purity: 99.69%

Synonyms: SNDX-50469

Target:

Epigenetic Reader Domain Apoptosis

Research Areas:

Cancer

VTP50469 is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a K_i of 104 pM. VTP50469 has potently anti-leukemia activity .

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VTP50469 fumarate

13 Cited Publications

Cat. No.: HY-114162A

CAS No.: 2169919-29-1

Purity: 99.79%

Synonyms: SNDX-50469 fumarate

Target:

Epigenetic Reader Domain Apoptosis

Research Areas:

Cancer

VTP50469 fumarate is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a K_i of 104 pM. VTP50469 fumarate has potently anti-leukemia activity .

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