43

EIDD-1931

43 Publications Verification

Cat. No.: HY-125033

CAS No.: 3258-02-4

Purity: 99.96%

Synonyms: β-D-N4-hydroxycytidine; NHC

Target:

CHIKV SARS-CoV Enterovirus HCV Topoisomerase

Research Areas:

Infection

EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) .

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21

Nafamostat mesylate

21 Cited Publications

Cat. No.: HY-B0190A

CAS No.: 82956-11-4

Synonyms: FUT-175

Target:

Flavivirus TNF Receptor NF-κB Apoptosis Ser/Thr Protease

Research Areas:

Infection Cancer

Nafamostat mesylate (FUT-175), an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat mesylate has anticancer and antivirus effect. Nafamostat mesylate induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat mesylate can be used in the development of the pathological thickening of the arterial wall .

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11

Bivalirudin

11 Cited Publications

Cat. No.: HY-P1929

CAS No.: 128270-60-0

Target:

Thrombin Interleukin Related RSV

Research Areas:

Infection Cardiovascular Disease Inflammation/Immunology

Bivalirudin, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin can be used for the research of thrombotic diseases and others .

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11

Bivalirudin TFA

11 Cited Publications

Cat. No.: HY-15664

CAS No.: 1191386-55-6

Purity: 99.89%

Target:

Thrombin Interleukin Related RSV

Research Areas:

Infection Cardiovascular Disease Inflammation/Immunology

Bivalirudin TFA, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin TFA inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin TFA also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin TFA can be used for the research of thrombotic diseases and others .

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8

Carmofur

8 Cited Publications

Cat. No.: HY-B0182

CAS No.: 61422-45-5

Synonyms: HCFU

Target:

Nucleoside Antimetabolite/Analog SARS-CoV Virus Protease FAAH Ceramidase Glutathione Peroxidase

Research Areas:

Infection Inflammation/Immunology Cancer

Carmofur (HCFU) is a rat recombinant acid ceramidase inhibitor with an IC₅₀ of 29 nM. Carmofur is also a protease inhibitor of SARS-CoV-2 main protease (Mpro), fatty acid amide hydrolase (FAAH) and N-acylethanolamine acid amidase (NAAA). Carmofur has anti-cancer, anti-inflammatory and anti-virus activities, and can be used for the study of COVID-19 and acute lung injury (ALI) .

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