1 Result for "

Anticancer agent367

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Anticancer agent367" in MCE Product Catalog:

Cat. No.: HY-189737
Target:  

Akt MMP Drug Derivative

Research Areas:  

Cancer

Anticancer agent-367 is a 3-hydroxy-3′,4′,5′-trimethoxyflavone derivative with selective cytotoxicity against osteosarcoma cells (IC50 = 14 μM). Anticancer agent-367 reduces AKT phosphorylation levels in 143B osteosarcoma cells and downregulates the expression of epithelial-mesenchymal transition-related genes such as ZEB1, MMP2, and MMP9. The combination of Anticancer agent-367 with Doxorubicin (HY-15142A) produces a synergistic antiproliferative effect on 143B cells. Anticancer agent-367 can be used in osteosarcoma-related research .
loading...
    loading...