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207 Results for "

Antithrombotic

" in MedChemExpress (MCE) Product Catalog:

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Clopidogrel hydrogen sulfate

33 Publications Verification

Cat. No.: HY-17459

CAS No.: 120202-66-6

Synonyms: (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate

Target:

Cytochrome P450 P2Y Receptor

Research Areas:

Cardiovascular Disease Cancer

Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC₅₀s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation ．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .

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RapaLink-1

14 Cited Publications

Cat. No.: HY-111373

CAS No.: 1887095-82-0

Purity: 99.92%

Target:

mTOR Autophagy

Research Areas:

Cancer

RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin (HY-10219) with MLN0128 (HY-13328, a second-generation mTOR kinase inhibitor) by an inert chemical linker. RapaLink-1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer-derived, activating mutants of mTOR. RapaLink-1 can cross the blood-brain barrier. RapaLink-1 binding to FKBP12 results in targeted and durable inhibition of mTORC1. RapaLink-1 plays an antithrombotic role in antiphospholipid syndrome by improving autophagy. Anticancer activity .

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