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95 Results for "

Antituberculosis activity

" in MedChemExpress (MCE) Product Catalog:

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Ethionamide

5 Cited Publications

Cat. No.: HY-B0276

CAS No.: 536-33-4

Synonyms: 2-Ethylthioisonicotinamide

Category:

Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics

Target:

Bacterial Antibiotic

Ethionamide (2-ethylthioisonicotinamide) is a second-line anti-tuberculosis antibiotic with antibacterial effect and oral activity .

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August 31

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Imidazole

3 Cited Publications

Cat. No.: HY-D0837

CAS No.: 288-32-4

Synonyms: Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

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Quabodepistat

3 Cited Publications

Cat. No.: HY-134940

CAS No.: 1883747-71-4

Purity: 98.00%

Synonyms: OPC-167832

Target:

Bacterial

Research Areas:

Infection Inflammation/Immunology

Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with an IC₅₀ of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis .

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