1 Result for "

Aplysinol

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Aplysinol" in MCE Product Catalog:

Aplysinol
Aplysinol
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Cat. No.: HY-N21832
CAS No.: 6790-64-3
Category:  

Natural Products Marine algae Marine natural products

Target:  

Toll-like Receptor (TLR) NF-κB

Aplysinol is an orally active TLR4 signaling pathway inhibitor. Aplysinol reduces the expression of CD14, MyD88, and NF-κB p65, and downregulates the expression and secretion of TNF-α protein as well as the secretion of IL-1β. Aplysinol restores the phagocytic activity of Kupffer cells and reduces plasma endotoxin levels. Aplysinol alleviates alcohol-induced liver histopathological changes and inhibits the elevation of liver injury biomarkers, and can be used for research related to alcoholic liver disease .
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