1 Result for "

Aurofusarin

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Aurofusarin" in MCE Product Catalog:

Cat. No.: HY-120805
CAS No.: 13191-64-5
Aurofusarin is a secondary metabolite . Aurofusarin catalytically inhibits topoisomerase II alpha, induces CYP1A1, p53, oxidative stress, DNA damage, and glutathione redox shift, intercalates into DNA, and causes S phase reduction accompanied by cytoskeletal/nuclear condensation. Aurofusarin disrupts intestinal epithelial barrier integrity, acts additively with deoxynivalenol, reduces mitochondrial activity, is cytotoxic to colon cells, and inhibits probiotic Gram-positive bacteria through outer membrane penetration without affecting Gram-negative bacteria. Aurofusarin can be used in research on colon cancer and bacterial infections .
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