88 Results for "

Autoimmune Disorder

" in MedChemExpress (MCE) Product Catalog:
Products (88)

88 Results for "Autoimmune Disorder" in MCE Product Catalog:

33
Upadacitinib
Upadacitinib
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33 Publications Verification
Cat. No.: HY-19569
CAS No.: 1310726-60-3
Synonyms: ABT-494
Target:  

JAK

Research Areas:  

Neurological Disease Inflammation/Immunology

Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research .
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7
Secalciferol
Secalciferol
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7 Cited Publications
Cat. No.: HY-32343
CAS No.: 55721-11-4
Synonyms: (24R)-24,25-Dihydroxyvitamin D3
Category:  

Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:  

Endogenous Metabolite VD/VDR

Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC50 value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders .
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6
Coumestrol
Coumestrol
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6 Cited Publications
Cat. No.: HY-N2335
CAS No.: 479-13-0
Category:  

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