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91 Results for "

Autophagosomes

" in MedChemExpress (MCE) Product Catalog:

Products (91)

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952

Bafilomycin A1

952 Publications Verification

Cat. No.: HY-100558

CAS No.: 88899-55-2

Purity: 99.95%

Synonyms: BafA1

Category:

Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Anticancer Disease Research Fields

Target:

Proton Pump Autophagy Antibiotic Bacterial Apoptosis

Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H ⁺-ATPase (V-ATPase) with IC₅₀ values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .

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305

Verteporfin

305 Cited Publications

Cat. No.: HY-B0146

CAS No.: 129497-78-5

Synonyms: CL 318952

Target:

YAP Apoptosis Autophagy Photosensitizer

Research Areas:

Cancer

Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis . Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation .

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226

MHY1485

226 Cited Publications

Cat. No.: HY-B0795

CAS No.: 326914-06-1

Target:

mTOR Autophagy

Research Areas:

Cancer

MHY1485 is a potent cell-permeable mTOR activator that targets the ATP domain of mTOR. MHY1485 inhibits autophagy by suppression of fusion between autophagosomes and lysosomes .

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