2 Results for "

Avoralstat

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Avoralstat" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-16735
CAS No.: 918407-35-9
Synonyms: BCX4161
Target:  

Kallikrein

Research Areas:  

Others

Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research .
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Cat. No.: HY-189696
Target:  

Drug Derivative

Research Areas:  

Cancer

XDTM13 is a biphenyl amide small-molecule TMPRSS2 inhibitor derived from the lead scaffold Avoralstat (HY-16735), with an IC50 of 3.60 nM. XDTM13 inhibits the autoproteolytic cleavage of TMPRSS2 protein in prostate cancer LNCaP cells and suppresses the migration and invasion ability of LNCaP cells. XDTM13 can be used for research on prostate cancer .
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