53 Results for "

B16F10 cell

" in MedChemExpress (MCE) Product Catalog:
Products (53)

53 Results for "B16F10 cell" in MCE Product Catalog:

4
CCZ01048 TFA
CCZ01048 TFA
0 Images
4 Cited Publications
Cat. No.: HY-P2336A
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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3
Fendiline hydrochloride
Fendiline hydrochloride
0 Images
3 Cited Publications
Cat. No.: HY-B0984
CAS No.: 13636-18-5
Target:  

Calcium Channel Ras STING Autophagy

Research Areas:  

Infection Cardiovascular Disease Cancer

Fendiline hydrochloride, a diphenylalkylamine type of antianginal agent, is an L-type calcium channel blocker (IC50 of 17 µM). Fendiline hydrochloride is also a selective K-Ras inhibitor, and has no effect on H-Ras and N-Ras. Fendiline hydrochloride inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM), inhibits K-Ras signal output and blocks the proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras. Fendiline hydrochloride is a STING agonist and is able to inhibit the growth of multiple refractory cold tumors (MC38, CT26 and B16F10) .
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3
Fendiline
Fendiline
0 Images
3 Cited Publications
Cat. No.: HY-B0984A
CAS No.: 13042-18-7
Target:  

Calcium Channel Ras STING Autophagy

Research Areas:  

Infection Cardiovascular Disease Cancer

Fendiline, a diphenylalkylamine type of antianginal agent, is an L-type calcium channel blocker (IC50 of 17 µM). Fendiline is also a selective K-Ras inhibitor, and has no effect on H-Ras and N-Ras. Fendiline inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM), inhibits K-Ras signal output and blocks the proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras. Fendiline is a STING agonist and is able to inhibit the growth of multiple refractory cold tumors (MC38, CT26 and B16F10) .
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1
Raspberry ketone glucoside
Raspberry ketone glucoside
0 Images
1 Cited Publications
Cat. No.: HY-N6069
CAS No.: 38963-94-9
Category:  

Ketones, Aldehydes, Acids Rosaceae Extract Plants 500 - Internal Server Error | MedChemExpress

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