186 Results for "

B2 receptor

" in MedChemExpress (MCE) Product Catalog:
Products (186)

186 Results for "B2 receptor" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-17446
CAS No.: 130308-48-4
Synonyms: HOE 140
Target:  

Bradykinin Receptor

Research Areas:  

Endocrinology

Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively .
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14
14 Publications Verification
Cat. No.: HY-108896
CAS No.: 138614-30-9
Purity:  99.85%
Synonyms: HOE 140 acetate
Target:  

Bradykinin Receptor

Research Areas:  

Inflammation/Immunology

Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively .
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2
2 Cited Publications
Cat. No.: HY-P0298A
CAS No.: 23827-91-0
[Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.
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2
2 Cited Publications
Cat. No.: HY-15039
CAS No.: 464930-42-5
Purity:  99.51%
SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist, with Kis of 0.48 nM and 0.73 nM for B1 kinin receptors of human fibroblast MRC5 and HEK cells expressing human B1 receptors, 481 nM and 358 nM for B2 receptors of guinea pig ileum membranes and CHO cells expressing human B1 receptor, respectively.
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2
2 Cited Publications
Cat. No.: HY-P73017
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EFNB2; Eph-Related receptor Tyrosine Kinase Ligand 5; Prev. EPLG5; MGC126226; Ephrin-B2; MGC126227; LERK5; MGC126228; HTKL; EPH-Related receptor Tyrosine Kinase Ligand 5; HTK Ligand; LERK-5; Htk-L; HTK-L; Ephrin B2; Ligand Of Eph-Related Kinase 5
Species:  
Mouse
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P73094
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2 Isoform C; receptor Tyrosine-Protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Proto-Oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Proto-Oncogene Neu; receptor Tyrosine-Protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; receptor Protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative Protein ERBB2; HER-2; C-Erb B2/Neu Protein; CD340; CD340 Antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type Cell Surface receptor HER2; Herstatin; Neuro/Glioblastoma Derived Oncogene Homolog; VSCN2; Human Epidermal Growth Factor receptor 2; MLN19; Metastatic Lymph Node Gene 19 Protein; TKR1; Erb-B2 receptor Tyrosine Kinase 2; MLN 19
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-12709A
CAS No.: 55974-42-0
Purity:  99.57%
ARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist (pKd values are 5.95, 7.41 and 7.56 at α2A, α2B, and α2C receptors respectively). ARC 239 dihydrochloride binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pKis of 5.6, 8.4, and 7.08, respectively .
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1
1 Cited Publications
Cat. No.: HY-105155
CAS No.: 159768-75-9
Purity:  99.60%
Synonyms: RMP 7
Target:  

Bradykinin Receptor

Research Areas:  

Cancer

Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM). Lobradimil increases the permeability of the BBB. Lobradimil can be used in the research of brain tumors .
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1
1 Cited Publications
Cat. No.: HY-W704574
CAS No.: 77102-28-4
Mergetpa is a reversible Arg-carboxypeptidase inhibitor with high affinity. Mergetpa reduces B1R. Mergetpa blocks the overexpression of IL-1β protein and mRNA in glucose-fed rats. Mergetpa significantly increases the expression of IL-1β protein in the renal cortex. Mergetpa is used to block the conversion of kinins and B2 receptor antagonists into metabolites lacking the C-terminal arginine. Mergetpa inhibits the time-dependent enhancement of the response of isolated rabbit aorta to bradykinin. Mergetpa preserves the chemotactic activity of full-length SDF-1α on cells. Mergetpa reverses hyperglycemia, excessive weight gain, elevated levels of oxidative stress markers and overexpression of inflammatory markers in glucose-fed rats .
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1
1 Cited Publications
Cat. No.: HY-12463A
CAS No.: 147568-66-9
Target:  

Adrenergic Receptor

Research Areas:  

Inflammation/Immunology

Carmoterol is a highly potent and selective long-acting β2-adrenergic receptor agonist with a pEC50 of 10.19. Carmoterol shows 53-fold higher affinity for β2-adrenergic receptors than for β1-adrenergic receptors. Carmoterol stimulates cyclic adenosine monophosphate accumulation, induces airway smooth muscle relaxation, inhibits bronchoconstriction, reduces thromboxane B2 release, and prolongs survival time. Carmoterol can be used in research related to asthma and chronic obstructive pulmonary disease (COPD) .
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1
1 Cited Publications
Cat. No.: HY-144064
CAS No.: 2703054-47-9
Purity:  99.37%
Target:  

Adenosine Receptor

Research Areas:  

Cancer

Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-P81722
Synonyms: B2BKR; B2BRA; B2R; BDKRB2; BK2 receptor; BK2R; BKR2; BR B2; BRB2; Kinin B2

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse

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1
1 Cited Publications
Cat. No.: HY-P77645
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: EFNB2; Eph-Related receptor Tyrosine Kinase Ligand 5; Prev. EPLG5; MGC126226; Ephrin-B2; MGC126227; LERK5; MGC126228; HTKL; EPH-Related receptor Tyrosine Kinase Ligand 5; HTK Ligand; LERK-5; Htk-L; HTK-L; Ephrin B2; Ligand Of Eph-Related Kinase 5
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P81085
Synonyms: Beta 2-adrenergic receptor; beta 2 Adrenergic receptor; ADRB2R; ADRBR; ADRB2_HUMAN; Adrenergic beta 2 receptor surface; B2AR; BAR; Beta 2 adrenoreceptor; BETA2AR; Catecholamine receptor; beta2-adrenergic receptor. β2-adrenergic receptor;

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-148088
CAS No.: 3027658-65-4
Purity:  98.04%
Target:  

Adenosine Receptor

Research Areas:  

Cancer

M1069 is a selective and orall active, dual A2A/A2B adenosine receptor antagonist with a selectivity of >100 fold against the A1 and A3 receptors. M1069 counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-148088A
CAS No.: 2459881-03-7
Purity:  98.92%
Target:  

Adenosine Receptor

Research Areas:  

Cancer

M1069 (free base) is a selective and orall active, dual A2A/A2B adenosine receptor antagonist with a selectivity of >100 fold against the A1 and A3 receptors. M1069 (free base) counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-P70601
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc Gamma receptor And Transporter; Neonatal Crystallizable Fc receptor FcRn Splice Variant 6; Neonatal Fc receptor; Neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; Neonatal Fragment Crystallizable Fc receptor FcRn; IgG Fc Fragment receptor Transporter Alpha Chain; Immunoglobulin receptor, Intestinal, Heavy Chain; IgG receptor FcRn Large Subunit P51; Neonatal Fc-receptor For Ig; FcgammaRn; FCRN Alpha-Chain; Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc receptor; FcRn Alpha Chain; Transmembrane Alpha Chain Of The Neonatal receptor; Alpha-Chain; Fc Fragment Of IgG, receptor, Transporter, Alpha; FCRN; Fc Fragment Of IgG receptor And Transporter; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P74177
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; receptor Protein-Tyrosine Kinase; receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein EGFR; Erb-B2 receptor Tyrosine Kinase 1; Epidermal Growth Factor; Proto-Oncogene C-ErbB-1; EGFR VIII; HER1; NISBD2; Epidermal Growth Factor receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); NNCIS; Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian); PIG61; Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog; MENA; Epidermal Growth Factor receptor Tyrosine Kinase Domain; Epidermal Growth Factor receptor; Epidermal Growth Factor receptor Variant EX12_15del
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70322
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SErbB3; HER3; P85-SErbB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ErbB-3 R31; Tyrosine Kinase-Type Cell Surface receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Recep
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P80116
Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody; Cell growth inhibiting protein 40 antibody; Cell proliferation inducing protein 61 antibody; EGF R antibody; EGFR antibody; EGFR_HUMAN antibody; Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody; Epidermal growth factor receptor antibody; erb-B2 receptor tyrosine kinase 1 antibody; ERBB antibody; ERBB1 antibody; Errp antibody; HER1 antibody; mENA antibody; NISBD2 antibody; Oncogen ERBB antibody; PIG61 antibody; Proto-oncogene c-ErbB-1 antibody; receptor tyrosine protein kinase ErbB 1 antibody; receptor tyrosine-protein kinase ErbB-1 antibody; SA7 antibody; Species antigen 7 antibody; Urogastrone antibody; v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody; wa2 antibody; Wa5 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC, mIHC

Reactivity:  

Human, Mouse, Rat

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