145 Results for "

BACE1,

" in MedChemExpress (MCE) Product Catalog:
Products (145)

145 Results for "BACE1," in MCE Product Catalog:

14
LY2811376
LY2811376
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14 Publications Verification
Cat. No.: HY-10472
CAS No.: 1194044-20-6
Purity:  99.62%
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

LY2811376 is the first orally available non-peptidic β-secretase (BACE1) inhibitor with IC50 of 239 nM-249 nM, that acts to decrease Aβ secretion with EC50 of 300 nM, and demonstrates to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin.
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7
Cornuside
Cornuside
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7 Cited Publications
Cat. No.: HY-N0631
CAS No.: 131189-57-6
Category:  

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