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9 Results for "

BDNF-TrkB

" in MedChemExpress (MCE) Product Catalog:

Products (9)

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AZD 2066

1 Cited Publications

Cat. No.: HY-110255

CAS No.: 934282-55-0

Purity: 99.8%

Target:

mGluR Calcium Channel Trk Receptor

Research Areas:

Neurological Disease

AZD-2066 is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 activates the BDNF/trkB signaling pathway. AZD 2066 can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .

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Phyllodulcin

Cat. No.: HY-W044525

CAS No.: 21499-23-0

Target:

Phosphodiesterase (PDE)

Research Areas:

Metabolic Disease Inflammation/Immunology

Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling .

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FLY26

Cat. No.: HY-172876

Target:

iGluR Reactive Oxygen Species (ROS) Trk Receptor

Research Areas:

Cardiovascular Disease

FLY26 is a selective partial GluN2B antagonist with an IC₅₀ value of 0.64 μM. FLY26 partially inhibits the GluN2B subunit of NMDA receptors, reduces calcium ion influx and reactive oxygen species (ROS) production and activates the BDNF/TrkB/CREB neuroprotective signaling pathway to alleviate neuronal excitotoxicity and mitochondrial dysfunction. FLY26 is promising for research of neurological deficits caused by cerebral ischemia-reperfusion injury .

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AZD 2066 hydrate

Cat. No.: HY-110255A

Target:

mGluR Calcium Channel Trk Receptor

Research Areas:

Neurological Disease

AZD-2066 hydrate is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrate activates the BDNF/trkB signaling pathway. AZD 2066 hydrate can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .

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AZD-2066 hydrochloride

Cat. No.: HY-110255B

CAS No.: 934338-70-2

Target:

mGluR Calcium Channel Trk Receptor

Research Areas:

Neurological Disease

AZD-2066 hydrochloride is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrochloride activates the BDNF/trkB signaling pathway. AZD 2066 hydrochloride can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .

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