3 Results for "

BFAR

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "BFAR" in MCE Product Catalog:

Cat. No.: HY-173599
Target:  

Molecular Glues PNPLA3

Research Areas:  

Metabolic Disease

NUV-244 is a molecular glue degrader of PNPLA3 I148M. NUV-244 induces degradation via the ubiquitin-proteasome system involving the E3 ligase BFAR. NUV-244 promotes 26S proteasome-dependent degradation of PNPLA3 I148M. NUV-244 restores lipid droplet morphology and cellular fitness in hepatocytes expressing PNPLA3 I148M. NUV-244 can be used in the research of metabolic dysfunction-associated fatty liver disease .
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Cat. No.: HY-RS01485
Research Areas:  

Others

BFAR Human Pre-designed siRNA Set A contains three designed siRNAs for BFAR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-170393
CAS No.: 353484-02-3
Target:  

JAK STAT

Research Areas:  

Cancer

iBFAR2, a BFAR inhibitor, restores the CD8+ TRM cell subset against solid tumors. iBFAR2 promotes JAK2-STAT1 association and STAT1 phosphorylation .
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