24

24 Publications Verification

Purity: ≥ 95%, as determined by reducing SDS-PAGE.

Synonyms: BMP2; SSFSC1; Prev. BMP2A; SSFSC; Bone Morphogenetic Protein 2A; BMP-2; BMP2 Protein; BDA2; Bone Morphogenetic Protein 2; BMP-2A

Species:

Rat Mouse Human

Source:

E. coli

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22

BMP-4 Protein, Human

22 Cited Publications

Cat. No.: HY-P7007

Purity: ≥ 95%, as determined by reducing SDS-PAGE.

Synonyms: BMP4; MCOPS6; Prev. BMP2B; OFC11; Bone Morphogenetic Protein 2B; BMP-4; Bone Morphogenetic Protein 4 Preproprotein; ZYME; Alternative Protein BMP4; DVR4; BMP2B1; Bone Morphogenetic Protein 4; BMP-2B

Species:

Human

Source:

E. coli

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6

AS2863619

6 Cited Publications

Cat. No.: HY-126675A

CAS No.: 2241300-51-4

Purity: 99.94%

Target:

STAT CDK Apoptosis TGF-beta/Smad

Research Areas:

Inflammation/Immunology

AS2863619 is an orally active CDK8/19 inhibitor that also inhibits BMP2, MDA5 and RIG-I receptors. AS2863619 targets Stat5a-CDK8/19 to promote the differentiation of CD4 ⁺ T cells into regulatory T cells and induce FOXP3 expression, thereby restoring immune homeostasis and establishing transplant immune tolerance. AS2863619 also enhances the BMP2/SMAD signaling pathway to promote osteogenic differentiation and inhibit adipogenic differentiation. AS2863619 exerts osteoprotective effects by alleviating inflammation-induced impairment of osteogenic function and inducing neutrophil apoptosis (apoptosis). AS2863619 can be applied to research in related fields such as periodontitis-induced bone defects .

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6

AS2863619 free base

6 Cited Publications

Cat. No.: HY-126675

CAS No.: 2241300-50-3

Purity: 99.68%

Target:

CDK TGF-beta/Smad Apoptosis STAT

Research Areas:

Inflammation/Immunology

AS2863619 free base is an orally active CDK8/19 inhibitor that also inhibits BMP2, MDA5 and RIG-I receptors. AS2863619 free base targets Stat5a-CDK8/19 to promote the differentiation of CD4 ⁺ T cells into regulatory T cells and induce FOXP3 expression, thereby restoring immune homeostasis and establishing transplant immune tolerance. AS2863619 free base also enhances the BMP2/SMAD signaling pathway to promote osteogenic differentiation and inhibit adipogenic differentiation. AS2863619 free base exerts osteoprotective effects by alleviating inflammation-induced impairment of osteogenic function and inducing neutrophil apoptosis (apoptosis). AS2863619 free base can be applied to research in related fields such as periodontitis-induced bone defects .

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5

BMP-4 Protein, Mouse (HEK293, Fc)

5 Cited Publications

Cat. No.: HY-P74379

Purity: ≥ 90%, as determined by reducing SDS-PAGE.

Synonyms: BMP4; MCOPS6; Prev. BMP2B; OFC11; Bone Morphogenetic Protein 2B; BMP-4; Bone Morphogenetic Protein 4 Preproprotein; ZYME; Alternative Protein BMP4; DVR4; BMP2B1; Bone Morphogenetic Protein 4; BMP-2B

Species:

Mouse

Source:

HEK293

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