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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
BODIPYS 1
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "BODIPYS 1" in MCE Product Catalog:
Cat. No.: HY-D3232
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BODIPYS1 is a near-infrared ratiometric fluorescent sensor and labile copper detection probe. BODIPYS1 possesses excitation-ratiometric copper-sensing capability, with the ratio of near-infrared emission under 600 nm excitation (710 nm) to that under 660 nm excitation, Fex600/Fex660, increasing from 2.8 to 10.7. BODIPYS1 is capable of tracking labile copper ions in mice .
Cat. No.: HY-D3233
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Ctrl-BODIPYS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BODIPYS1 has no fluorescent response to Cu + .
Cat. No.: HY-P11912
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Cat. No.: HY-D3145
CAS No.: 1680195-45-2
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BODIPY-1 is a lysosome-targeted temperature probe. BODIPY-1 relies on temperature-driven changes in microviscosity and hydrophobicity, as well as its own lysosome-targeting morpholine group; at room temperature, its fluorescence is quenched by intramolecular rotation, but upon heating, the oligo (ethylene glycol) groups undergo thermal dehydration, increasing the microviscosity and hydrophobicity around the fluorophore, which disfavors photoinduced electron transfer (PET) and progressively enhances fluorescence, while aggregates formed above its phase transition temperature also produce fluorescence. In neutral aqueous solution, its detection wavelengths are Ex/Em = 490/542 nm at 25°C and Ex/Em = 490/557 nm at 55°C, and the emission maximum at ~557 nm at high temperature shows more than a 3-fold enhancement .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
