53 Results for "

BV-2 cells

" in MedChemExpress (MCE) Product Catalog:
Products (53)

53 Results for "BV-2 cells" in MCE Product Catalog:

4
CHPG
CHPG
0 Images
4 Cited Publications
Cat. No.: HY-101364
CAS No.: 170846-74-9
Purity:  99.51%
Target:  

mGluR NF-κB ERK Akt

Research Areas:  

Cardiovascular Disease Inflammation/Immunology

CHPG is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells . CHPG protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways .
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4
CHPG sodium salt
CHPG sodium salt
0 Images
4 Cited Publications
Cat. No.: HY-101364A
CAS No.: 1303993-73-8
Purity:  99.25%
Target:  

mGluR NF-κB ERK Akt

Research Areas:  

Neurological Disease Inflammation/Immunology

CHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells . CHPG sodium salt protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways. .
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2
Gliquidone
Gliquidone
0 Images
2 Cited Publications
Cat. No.: HY-B1114
CAS No.: 33342-05-1
Synonyms: AR-DF 26
Target:  

Potassium Channel Free Radical Scavengers ERK STAT NF-κB COX Interleukin Related Reactive Oxygen Species (ROS)

Research Areas:  

Metabolic Disease

Gliquidone can bind to the pancreatic β-cells and increases insulin release to regulate blood glucose levels. Gliquidone significantly decreases LPS (HY-D1056)-induced proinflammatory responses and inhibits ERK/STAT3/NF-κB phosphorylation in BV2 microglial cells. Gliquidone can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone also exhibits good anticancer activity in lung carcinoma cells. Gliquidone has antioxidant property. Gliquidone can be studied in research for type 2 diabetes and cancers .
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Bullatine A
Bullatine A
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Cat. No.: HY-N5025
CAS No.: 1354-84-3
Category:  

Alkaloids Piperidine Alkaloids Plants Aconitum carmichaeli Debx. Extract Disease Research Fields Inflammation/Immunology Ranunculaceae Extract

Target:  

P2X Receptor Apoptosis ERK p38 MAPK c-Myc NF-κB Reactive Oxygen Species (ROS)

Bullatine A, a diterpenoid alkaloid, is a potent P2X7 antagonist. Bullatine A possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A inhibits ATP-induced BV-2 cell death/apoptosis and P2X receptor-mediated inflammatory responses. Bullatine A suppresses glioma cell growth by targeting SIRT6. Bullatine A specifically attenuates pain hypersensitivity in rats. Bullatine A attenuates LPS (HY-D1056)-induced systemic inflammatory response by inhibiting the ROS/JNK/NF-κB pathway in mice. Bullatine A improves despair behavior in Chronic chronic social defeat stress (CSDS) mice. Bullatine A can be used for the study of inflammation, glioblastoma (GBM) and depression .
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Shizukaol B
Shizukaol B
0 Images
Cat. No.: HY-N8371
CAS No.: 142279-40-1
Category:  

Chloranthaceae Extract Terpenoids Sesquiterpenes Plants 500 - Internal Server Error | MedChemExpress

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