14 Results for "

BV2 microglia

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "BV2 microglia" in MCE Product Catalog:

TG8-260
TG8-260
0 Images
Cat. No.: HY-164049
CAS No.: 2490544-50-6
Target:  

Prostaglandin Receptor

Research Areas:  

Inflammation/Immunology

TG8-260 is a second-generation EP2 antagonist developed to alleviate the pathology of central nervous system and peripheral diseases driven by inflammation. TG8-260 can reduce neuroinflammation and gliosis in the hippocampus of rats after pilocarpine-induced persistent epileptic status. Pharmacokinetic data of TG8-260 showed that its plasma half-life was 2.14 hours and its oral bioavailability was 77.3%. TG8-260 is also a potent inhibitor of CYP450 and shows antagonistic activity in inhibiting EP2 receptor-mediated inflammatory gene expression in BV2-hEP2 microglia, which is suitable for studying anti-inflammatory pathways in animal models of peripheral inflammatory diseases .
loading...
    loading...
View All Sizes
(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid
(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid
0 Images
Cat. No.: HY-N8090
CAS No.: 1961358-02-0
Category:  

Triterpenes Microorganisms Terpenoids Disease Research Fields Inflammation/Immunology

Target:  

NO Synthase

(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoids, exhibits obvious NO inhibitory activity on n LPS-induced BV-2 microglia cells with an IC50 of 9.55 uM. (3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid has anti-inflammatory activities .
loading...
    loading...
View All Sizes
Dichotomine B
Dichotomine B
0 Images
Cat. No.: HY-N10386
CAS No.: 755036-41-0
Category:  

Alkaloids Caryophyllaceae Extract 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.