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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
Beta-Carboline
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "Beta-Carboline" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: Keramamine A hydrochloride
1
Cat. No.: HY-W008566
CAS No.: 244-63-3
Synonyms: Norharman; β-Carboline
Category:
Alkaloids Simaroubaceae Extract Plant Other Diseases Pyridine Alkaloids Disease Research Fields Indole Alkaloids
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Cat. No.: HY-20696
CAS No.: 16502-01-5
Synonyms: Tryptoline
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Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM .
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Ethyl β-carboline-3-carboxylate (fl-CCE) is a ligand and short-acting antagonist of benzodiazepine receptors. Ethyl β-carboline-3-carboxylate did not affect cerebellar cGMP levels when used alone, but when taken together with Diazepam, it significantly inhibited the cGMP levels that were upregulated by Diazepam .
Synonyms: Keramamine A
Cat. No.: HY-W049881
CAS No.: 2521-07-5
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9-Methyl-β-carboline is a monoamine oxidase inhibitor and dopaminergic modulator, with an IC50 of 1 μM against human MAO-A and an IC50 of 15.5 μM against human MAO-B. 9-Methyl-β-carboline possesses cognitive enhancement potential and can cross the blood-brain barrier. 9-Methyl-β-carboline increases dopamine levels by inhibiting monoamine oxidase activity and microglial proliferation. 9-Methyl-β-carboline activates PKA/PKC and mitochondrial respiratory chain complex I, promotes neurotrophic factor expression and reduces α-synuclein (α-synuclein) levels, thereby reversing neurotoxin-induced dopaminergic neuron damage. 9-Methyl-β-carboline also regulates the PI3K pathway and exerts an anti-proliferative effect on astrocytes. 9-Methyl-β-carboline is widely used in Parkinson's disease-related studies .
Cat. No.: HY-W130965
CAS No.: 20127-63-3
Category:
Alkaloids Simaroubaceae Extract Plant Pyridine Alkaloids Picrasma quassioides(D．Don)Benn． Extract
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Cat. No.: HY-N3711
CAS No.: 26585-13-7
Category:
Zygophyllaceae Extract Pyridine Alkaloids Peganum harmala L. Extract Alkaloids Plant Monophenols Nitrariaceae Extract Other Diseases Phenols Disease Research Fields
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Cat. No.: HY-P5189A
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Cat. No.: HY-N10450
CAS No.: 72755-19-2
Synonyms: 1-Ethoxycarbonyl-β-Carboline
Category:
Alkaloids Simaroubaceae Extract Plant Picrasma quassioides(D．Don)Benn． Extract Indole Alkaloids
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ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity .
Cat. No.: HY-W060074
CAS No.: 50892-83-6
Category:
Infection Alkaloids Pyridine Alkaloids Microorganism Disease Research Fields Indole Alkaloids
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Cat. No.: HY-N11016
CAS No.: 55854-60-9
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Cat. No.: HY-174156
CAS No.: 3092616-03-7
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Y2641, a etrahydro-β-carboline derivative, is an orally active dual RANKL/TNF-α inhibitor with Kd values of 3.984 μM and 18.59 μM for RANKL and TNF-α, respectively. Y2641 inhibits RANKL-induced osteoclastogenic and has anti-inflammatory and cartilage destruction. Y2641 can be used for study of osteoarthritis .
Cat. No.: HY-N9009
CAS No.: 1408311-12-5
Category:
Alkaloids Animal Other Diseases Pyridine Alkaloids Disease Research Fields Indole Alkaloids
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1,2,3,4-Tetrahydro-β-carboline-1-carboxylic acid is a chemical used on the study of neurodegenerative diseases .
Cat. No.: HY-N10960
CAS No.: 66154-37-8
Category:
Alkaloids Plant Caryophyllaceae Extract Pyrrole Alkaloids Pyridine Alkaloids Stellaria dichotoma var. lanceolata Bge. Extract
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
