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66 Results for "

C/EBP

" in MedChemExpress (MCE) Product Catalog:

Products (66)

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Eicosapentaenoic Acid

33 Publications Verification

Cat. No.: HY-B0660

CAS No.: 10417-94-4

Synonyms: EPA; Timnodonic acid

Category:

Human Gut Microbiota Metabolites Neurological Disease Ketones, Aldehydes, Acids Marine natural products Endogenous metabolite Disease Research Fields Cancer

Target:

Endogenous Metabolite Histone Demethylase

Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

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Eicosapentaenoic Acid sodium

33 Publications Verification

Cat. No.: HY-W011269

CAS No.: 73167-03-0

Synonyms: EPA sodium; Timnodonic acid sodium

Category:

Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite Histone Demethylase

Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .

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SGI-1776 free base

12 Cited Publications

Cat. No.: HY-13287

CAS No.: 1025065-69-3

Purity: 99.35%

Target:

Pim Apoptosis FLT3 PPAR FASTK STAT Mitochondrial Metabolism DNA/RNA Synthesis Bcl-2 Family

SGI-1776 free base is an orally active Pim kinase and FLT3 inhibitor with IC₅₀ values of 7 nM, 363 nM, 69 nM, and 44 nM for Pim-1, Pim-2, Pim-3, and FLT3, respectively. SGI-1776 free base downregulates C/EBP-α, PPAR-γ, FAS, Leptin, and RANTES, and decreases STAT-3 phosphorylation. SGI-1776 free base induces Apoptosis, cell cycle arrest, mitochondrial depolarization, and reduces RNA synthesis, protein synthesis, and Mcl-1. SGI-1776 free base inhibits adipogenesis and lipid accumulation. SGI-1776 free base has anticancer activity against leukemia .

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BiP inducer X

7 Cited Publications

Cat. No.: HY-110188

CAS No.: 101714-41-4

Purity: 99.88%

Target:

Apoptosis

Research Areas:

Neurological Disease

BiP inducer X, a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78, is an effective ER (endoplasmic reticulum) stress inhibitor. BiP inducer X preferentially induces BiP with slight inductions of GRP94, calreticulin, and C/EBP homologous protein. BiP inducer X protects neurons from ER stress .

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