113 Results for "

C6 cells

" in MedChemExpress (MCE) Product Catalog:
Products (113)

113 Results for "C6 cells" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-N1127
CAS No.: 520-32-1
Tricin is a natural flavonoid found in large amounts in wheat. Tricin inhibits HCMV replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells by upregulating the expression of FAK-targeting microRNA-7 .
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4
4 Cited Publications
Cat. No.: HY-19542
CAS No.: 124753-97-5
Synonyms: C6-Cer; N-Hexanoylsphingosine
Target:  

Apoptosis

Research Areas:  

Cancer

C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
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2
2 Cited Publications
Cat. No.: HY-112495
CAS No.: 1799506-06-1
Purity:  99.93%
Synonyms: HaloPROTAC 2
Research Areas:  

Cancer

VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
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1
1 Cited Publications
Cat. No.: HY-103605
CAS No.: 1835705-55-9
Purity:  97.01%
Synonyms: VH032-C6-PEG3-C4-Cl; VHL Ligand-Linker Conjugates 12; E3 ligase Ligand-Linker Conjugates 8
Research Areas:  

Cancer

(S,R,S)-AHPC-C6-PEG3-C4-Cl (VH032-C6-PEG3-C4-Cl) is a conjugate of ligands for E3 and 20-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-C6-PEG3-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and an alkyl/ether-based linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
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1
1 Cited Publications
Cat. No.: HY-119402
CAS No.: 2130878-25-8
Purity:  99.14%
Synonyms: BCL6-IN-8c
Target:  

Bcl-2 Family

Research Areas:  

Cancer

TP-021 (BCL6-IN-8c), a chemical probe, is a potent and orally active B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor with an IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent assay .
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Cat. No.: HY-N0455AS8
CAS No.: 202468-25-5
Synonyms: (S)-(+)-Arginine-13C6,15N4 hydrochloride
L-Arginine- 13C6, 15N4 (hydrochloride) is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
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Cat. No.: HY-N1428S1
CAS No.: 287389-42-8
Citric acid- 13C6 is the 13C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
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Cat. No.: HY-N0455AS6
CAS No.: 201740-91-2
Synonyms: (S)-(+)-Arginine-13C6 hydrochloride
L-Arginine- 13C6 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
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Cat. No.: HY-W356116
CAS No.: 94885-02-6
Synonyms: Nbd-ceramide
Target:  

Fluorescent Dye

Research Areas:  

Others

C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism .
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Cat. No.: HY-N2038
CAS No.: 1178-24-1
3,5,6,7,8,3',4'-Heptemthoxyflavone, a flavonoid from satsuma peel, is an orally available CREB activator with anti-tumor and anti-neuroinflammatory activity. 3,5,6,7,8,3',4'-Heptemthoxyflavone inhibits collagenase activity and increases the content of type I procollagen in human dermal fibroblast neoblast (HDFn) cells. 3,5,6,7,8,3',4'-Heptemthoxyflavone induces brain-derived neurotrophic factor (BDNF) expression through the cAMP/ERK/CREB signaling pathway and reduces phosphodiesterase activity in C6 glioma .
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Cat. No.: HY-N6076
CAS No.: 139726-35-5
Tenuifoliside A is isolated from Polygala tenuifolia, has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits its neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells .
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Cat. No.: HY-103608
CAS No.: 1835705-61-7
Purity:  99.89%
Synonyms: VHL Ligand-Linker Conjugates 11; E3 ligase Ligand-Linker Conjugates 11
Research Areas:  

Cancer

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
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Cat. No.: HY-18569S4
CAS No.: 100849-36-3
Synonyms: Indole-3-acetic acid-13C6; 3-IAA-13C6
3-Indoleacetic acid- 13C6 (Indole-3-acetic acid- 13C6) is the 13C-labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
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Cat. No.: HY-B0166S8
CAS No.: 1331939-77-5
Synonyms: L-Ascorbate-1; Vitamin C-13C6-1
L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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Cat. No.: HY-P990634

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

NEO-201 is a humanized antibody expressed in CHO cells that targets CEACAM6/CD66c. NEO-201 features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.48 kDa. The isotype control for NEO-201 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-Y0075
CAS No.: 66-99-9
2-Naphthaldehyde belongs to naphthalene-based bis-aromatic aldehyde compounds. 2-Naphthaldehyde scavenges DPPH and ABTS + free radicals, and exerts reductive effects by donating hydrogen atoms to interrupt free radical chain reactions. 2-Naphthaldehyde inhibits the growth and proliferation of colon cancer cells. 2-Naphthaldehyde serves as a substrate for NAD +-dependent salicylaldehyde dehydrogenase from Pseudomonas strain C6 and is catalytically oxidized. 2-Naphthaldehyde acts as a precursor material for the chemical synthesis of antioxidant Schiff bases .
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Cat. No.: HY-D1432
FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor .
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Cat. No.: HY-15036S1
CAS No.: 1261393-71-8
Purity:  99.90%
Diclofenac- 13C6 is the 13C6 labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
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Cat. No.: HY-B0150S2
CAS No.: 2749910-55-0
Synonyms: Niacinamide-13C6; Nicotinic acid amide-13C6
Nicotinamide- 13C6 is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
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Cat. No.: HY-W014375S4
Synonyms: (±)-Arginine-13C6,15N4 hydrochloride
DL-Arginine- 13C6, 15N4 hydrochloride is 13C and 15N-labeled DL-Arginine hydrochloride (HY-W014375). DL-Arginine ((±)-Arginine) hydrochloride is the racemic compound of L-Arginine (HY-N0455) and D-Arginine (HY-W016781). Arginine is an essential amino acid that requires additional supplementation in traumatic or diseased conditions. Arginine is involved in T cell activation, proliferation, and differentiation, and affects the function of immune cells .
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