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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
CA9
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "CA9" in MCE Product Catalog:
2
Target:
Research Areas:
Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells .
Cat. No.: HY-W074975
CAS No.: 14949-00-9
Synonyms: 5-Amino-1,3,4-thiadiazole-2-sulfonamide
Target:
Research Areas:
CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is a selective inhibitor of carbonic anhydrase B (HCA-B) and isoforms I, II, IV, and VII. CL 5343 has a Ki of 7.9 nM for hCA II. CL 5343 acts as a CA9 ligand to achieve targeted delivery of maytansine to the cell membrane of SKRC52 renal cancer cells. CL 5343 is useful in the development of therapeutics for diseases associated with CA overactivity, such as glaucoma, epilepsy, and cancer .
Cat. No.: HY-RS01776
Target:
Research Areas:
CA9 Human Pre-designed siRNA Set A contains three designed siRNAs for CA9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-123009
CAS No.: 927823-01-6
Target:
HIF/HIF Prolyl-Hydroxylase Histone Acetyltransferase Apoptosis Carbonic Anhydrase VEGFR GLUT
Research Areas:
KCN1 is a p300/HIF-1α interaction inhibitor with a Kd value of 345 nM for p300-CH1. KCN1 binds to the CH1 domain of p300, blocks the assembly of the p300/HIF-1α complex, and disrupts the HIF-1α-p300/CBP interaction. KCN1 inhibits cancer cell growth, induces cancer cell cycle arrest and apoptosis. KCN1 inhibits β-galactosidase activity and downregulates the expression of VEGF, Glut1, CA9 and CAIX. KCN1 exerts anticancer activity in mouse tumor xenograft models. KCN1 can be used in research related to malignant glioma, pancreatic cancer and metastatic uveal melanoma .
Research Areas:
Benzthiazide (Standard) is the analytical standard of Benzthiazide. This product is intended for research and analytical applications. Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells .
Cat. No.: HY-W074975R
CAS No.: 14949-00-9
Synonyms: 5-Amino-1,3,4-thiadiazole-2-sulfonamide (Standard)
Research Areas:
CL 5343 (Standard) is the analytical standard of CL 5343. This product is intended for research and analytical applications. CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is an inhibitor of human carbonic anhydrase B (HCA-B). CL 5343 can serve as a CA9 ligand to achieve the targeted delivery of maytansinoid to the cell membrane of SKRC52 renal cancer cells .
Cat. No.: HY-P85663
Synonyms: CA9; G250; MN; CArbonic anhydrase 9; CArbonate dehydratase IX; CArbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell CArcinoma-associated antigen G250; RCC-associated antigen G250; pMW1
Cat. No.: HY-RS01913
Target:
Research Areas:
Car9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Car9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70064
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA9; CArbonate Dehydratase IX; CArbonic Anhydrase 9; CArbonic Dehydratase; CAIX; Membrane Antigen MN; MN; P54/58N; CArbonic Anhydrase IX; CA-IX; Renal Cell CArcinoma-Associated Antigen G250; PMW1; RCC-Associated Protein G250; CArbonic Anhydrase; RCC-Assoc
Species:
Human
Source:
HEK293
Cat. No.: HY-P78396
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CA9; CArbonate Dehydratase IX; CArbonic Anhydrase 9; CArbonic Dehydratase; CAIX; Membrane Antigen MN; MN; P54/58N; CArbonic Anhydrase IX; CA-IX; Renal Cell CArcinoma-Associated Antigen G250; PMW1; RCC-Associated Protein G250; CArbonic Anhydrase; RCC-Assoc
Species:
Human
Source:
HEK293
Cat. No.: HY-186248
CAS No.: 329719-71-3
Target:
Carbonic Anhydrase HIF/HIF Prolyl-Hydroxylase Bcl-2 Family Caspase PARP Apoptosis Reactive Oxygen Species (ROS)
Research Areas:
BCS12 is a CAIX inhibitor. BCS12 inhibits the viability of cancer cells under hypoxic conditions. BCS12 elevates ROS levels and suppresses the expression of HIF-1α and CA9. BCS12 downregulates Bcl-2, activates caspase-9, caspase-3, caspase-7 and Bax, and induces PARP cleavage and apoptosis. BCS12 reduces tumor burden, increases the number of apoptotic nuclei and restores tissue structure in rats bearing breast tumors. BCS12 can be used in research related to triple-negative breast cancer .
Cat. No.: HY-P700882
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA9; CArbonate Dehydratase IX; CArbonic Anhydrase 9; CArbonic Dehydratase; CAIX; Membrane Antigen MN; MN; P54/58N; CArbonic Anhydrase IX; CA-IX; Renal Cell CArcinoma-Associated Antigen G250; PMW1; RCC-Associated Protein G250; CArbonic Anhydrase; RCC-Assoc
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P704425
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CA9; CArbonate Dehydratase IX; CArbonic Anhydrase 9; CArbonic Dehydratase; CAIX; Membrane Antigen MN; MN; P54/58N; CArbonic Anhydrase IX; CA-IX; Renal Cell CArcinoma-Associated Antigen G250; PMW1; RCC-Associated Protein G250; CArbonic Anhydrase; RCC-Assoc
Species:
Human
Source:
HEK293
Cat. No.: HY-P72348
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA9; CArbonate Dehydratase IX; CArbonic Anhydrase 9; CArbonic Dehydratase; CAIX; Membrane Antigen MN; MN; P54/58N; CArbonic Anhydrase IX; CA-IX; Renal Cell CArcinoma-Associated Antigen G250; PMW1; RCC-Associated Protein G250; CArbonic Anhydrase; RCC-Assoc
Species:
Human
Source:
HEK293
Cat. No.: HY-P77585
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CA9; CArbonate Dehydratase IX; CArbonic Anhydrase 9; CArbonic Dehydratase; CAIX; Membrane Antigen MN; MN; P54/58N; CArbonic Anhydrase IX; CA-IX; Renal Cell CArcinoma-Associated Antigen G250; PMW1; RCC-Associated Protein G250; CArbonic Anhydrase; RCC-Assoc
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P991887
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
