6

6 Publications Verification

Synonyms: (-)-(E)-Caryophyllene; (−)-β-caryophyllene; (−)-trans-Caryophyllene

Category:

Neurological Disease Anti-aging Plants Other Families Extract Endogenous metabolite Infection Terpenoids Sesquiterpenes Disease Research Fields Cancer

Target:

Environmental Pollutants Endogenous Metabolite Cannabinoid Receptor

β-Caryophyllene is a CB2 receptor agonist.

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2

MDA 19

2 Cited Publications

Cat. No.: HY-15451

CAS No.: 1048973-47-2

Purity: 99.26%

Synonyms: BZO-HEXOXIZID

Target:

Cannabinoid Receptor

Research Areas:

Neurological Disease

MDA 19 is a potent and selective agonist of human cannabinoid receptor 2 (CB2), with a K_i of 43.3 nM. MDA 19 has antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity .

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2

Olorinab

2 Cited Publications

Cat. No.: HY-111110

CAS No.: 1268881-20-4

Purity: 99.29%

Synonyms: APD 371

Target:

Cannabinoid Receptor

Research Areas:

Neurological Disease

Olorinab (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB₂) agonist, with an EC₅₀ of 6.2 nM for hCB₂.

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1

N-Arachidonylglycine

1 Cited Publications

Cat. No.: HY-103332

CAS No.: 179113-91-8

Purity: 98.90%

Synonyms: NA-Gly

Category:

Alkaloids Other Alkaloids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

GlyT Endogenous Metabolite

N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC₅₀ = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC₅₀ = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration .

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1

LY2828360

1 Cited Publications

Cat. No.: HY-16642A

CAS No.: 1231220-79-3

Target:

Cannabinoid Receptor

Research Areas:

Neurological Disease

LY2828360 is a slowly acting but efficacious G protein-biased cannabinoid (CB₂) agonist, inhibiting cAMP accumulation and activating ERK1/2 signaling.

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1

AZD1940

1 Cited Publications

Cat. No.: HY-119104

CAS No.: 881413-29-2

Purity: 99.58%

Target:

Cannabinoid Receptor

Research Areas:

Neurological Disease

AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pK_i values of 7.93 and 9.06 for human CB1R and CB2R, respectively. AZD1940 shows a robust analgesia action .

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1

GP1a

1 Cited Publications

Cat. No.: HY-110050

CAS No.: 511532-96-0

Purity: 99.66%

Target:

Cannabinoid Receptor

Research Areas:

Neurological Disease Inflammation/Immunology

GP1a is a potent agonist of cannabinoid receptor 2 (CB2). Gp1a is beneficial to skin wound healing. GP1a inhibits inflammation and fibrogenesis while promoting re-epithelialization .

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1

β-Caryophyllene (Standard)

1 Cited Publications

Cat. No.: HY-N1415R

CAS No.: 87-44-5

Synonyms: (-)-(E)-Caryophyllene(Standard); (−)-β-caryophyllene(Standard); (−)-trans-Caryophyllene (Standard)

Category:

Infection Neurological Disease Anti-aging Terpenoids Plants Other Families Extract Endogenous metabolite Disease Research Fields Cancer

Target:

Reference Standards Cannabinoid Receptor Endogenous Metabolite

β-Caryophyllene (Standard) is the analytical standard of β-Caryophyllene. This product is intended for research and analytical applications. β-Caryophyllene is a CB2 receptor agonist.

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1

Tedalinab

1 Cited Publications

Cat. No.: HY-14900

CAS No.: 916591-01-0

Purity: 99.94%

Synonyms: GRC-10693

Target:

Cannabinoid Receptor

Research Areas:

Inflammation/Immunology

Tedalinab (GRC-10693) is a potent, orally active, and selective cannabinoid receptor 2 (CB2) agonist. Tedalinab has >4700-fold functional selectivity for CB2 over CB1. Tedalinab has potential for neuropathic pain and osteoarthritis treatment .

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