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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
CBM
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "CBM" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases .
Cat. No.: HY-W250721A
CAS No.: 9007-20-9
Synonyms: CBM 940
Cat. No.: HY-W250721
CAS No.: 9007-20-9
Synonyms: CBM 980
Target:
Molecular Glues IKZF Family Casein Kinase Phosphodiesterase (PDE) MDM-2/p53 NF-κB Interleukin Related Apoptosis
Research Areas:
FPFT-2216 is an orally active Molecular glue degrader targeting IKZF1, IKZF3, CK-1α, and PDE6D, with a DC50 of 8 nM against PDE6D. FPFT-2216 mediates ubiquitin-proteasome degradation via the CRL4 CRBN E3 ubiquitin ligase complex and interacts with the non-isoprenoid-binding region of PDE6D. FPFT-2216 activates the p53 signaling pathway, inhibits the CBM complex/NF-κB pathway, upregulates IL-2, suppresses IL-1β and IL-6, and induces tumor cell Apoptosis. FPFT-2216 exhibits anticancer activity against multiple myeloma and lymphoma. FPFT-2216 can be used in research related to multiple myeloma, lymphoma, acute lymphoblastic leukemia, acute myeloid leukemia, pancreatic ductal adenocarcinoma, non-small cell lung cancer, and gastric adenocarcinoma .
Cat. No.: HY-W250721B
CAS No.: 9007-20-9
Synonyms: CBM 934
Cat. No.: HY-W250721C
CAS No.: 9007-20-9
Synonyms: CBM 941
Cat. No.: HY-W250721J
CAS No.: 9007-20-9
Synonyms: CBM 960
Cat. No.: HY-W250721H
CAS No.: 9007-20-9
Synonyms: CBM 970
Cat. No.: HY-W250721K
CAS No.: 9007-20-9
Synonyms: CBM 996
Cat. No.: HY-W250721L
CAS No.: 9007-20-9
Synonyms: CBM 676
Cat. No.: HY-121914
CAS No.: 66774-02-5
Synonyms: o-Chlorotriphenylmethanol
Target:
Research Areas:
(2-Chlorophenyl)diphenylmethanol (UCL 1880) is an analog of the metabolite 2-chlorophen-diphenyl-methanol (CBM) of 2-chlorophenyl, The IC50 for sI(AHP) inhibition is 1-2 μM. (2-chlorophenyl)diphenylmethanol is a weak Ca 2+ channel blocker .
Cat. No.: HY-179305
Target:
Research Areas:
CBM-4077 is a PROTAC E3 ligand that can be used for synthesis of PROTACs, such as BCL6-760 (HY-178777). BCL6-760 is a potent BCL6 PROTAC degrader with anti-tumor activity .
Cat. No.: HY-W044285
CAS No.: 324017-22-3
Target:
Research Areas:
Cat. No.: HY-W250721I
CAS No.: 9007-20-9
Synonyms: CBM 990
Cat. No.: HY-136967
CAS No.: 81968-16-3
Synonyms: CBM36-733
Target:
Research Areas:
Mergocriptine (CBM36-733) is a dopamine receptor agonist and SARS-CoV-2 M pro ligand. Mergocriptine regulates ambulatory activity .
Cat. No.: HY-121914R
CAS No.: 66774-02-5
Synonyms: o-Chlorotriphenylmethanol (Standard)
Target:
Research Areas:
(2-Chlorophenyl)diphenylmethanol (Standard) is the analytical standard of (2-Chlorophenyl)diphenylmethanol. This product is intended for research and analytical applications. (2-Chlorophenyl)diphenylmethanol (UCL 1880) is an analog of the metabolite 2-chlorophen-diphenyl-methanol (CBM) of 2-chlorophenyl, The IC50 for sI(AHP) inhibition is 1-2 μM. (2-chlorophenyl)diphenylmethanol is a weak Ca2+ channel blocker .
Cat. No.: HY-106796
CAS No.: 146452-37-1
Synonyms: CBM 11
Target:
Research Areas:
(-)-(S)-Bromofosfamide (CBM 11) is an anti-cancer agent and a bromine-substituted IFO analog. (-)-(S)-Bromofosfamide can be studied in research on non-small cell lung cancer .
Cat. No.: HY-W419324
CAS No.: 324017-23-4
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
