16 Results for "

CD-1 mouse

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "CD-1 mouse" in MCE Product Catalog:

Cat. No.: HY-P990273

Target:  

CD38 ERK CD1 Apoptosis

Research Areas:  

Cancer

Anti-Mouse CD38 Antibody (NIMR5) is an anti-mouse CD38 IgG2a monoclonal antibody. Anti-Mouse CD38 Antibody (NIMR5) can activate the ERK signaling pathway and promote cell apoptosis. Anti-Mouse CD38 Antibody (NIMR5) can restore T cell function. Anti-Mouse CD38 Antibody (NIMR5) upregulates the expression of CD1d protein and enhances spleen cell proliferation, dendritic cell (DC) and natural killer T cell (NKT) expansion. Anti-Mouse CD38 Antibody (NIMR5) can be used for researches on cancer and immunology such as melanoma and colon cancer .
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Cat. No.: HY-P990287

Target:  

CD1

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD1d Antibody (19G11) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (19G11) can neutralize CD1d and inhibit the activation of invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (19G11) can be used for the researches of inflammation and immunology, such as colitis .
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Cat. No.: HY-162484
CAS No.: 3089845-68-8
Target:  

SARS-CoV Virus Protease

Research Areas:  

Infection

GZNL-P36 is an orally active inhibitor for SARS-CoV-2 papain-like protease (PL pro), with an IC50 of 6.45 nM. GZNL-P36 inhibits SARS-CoV and its variants with EC50 range from 58.2 nM to 2.66 μM. GZNL-P36 exhibits a peak plasma concentration Cmax of 549 ng/mL, a half-life T1/2 of 1.45 h and a bioavailability of 74.7% in CD-1 mouse. GZNL-P36 exhibits antiviral activity in SARS-CoV-2 XXB.1 infection in mouse .
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Cat. No.: HY-P990807

Target:  

CD1

Anti-Mouse CD1d Antibody (20H2 (HB323)) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (20H2 (HB323)) can block CD1d and neutralize invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (20H2 (HB323)) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma, L. monocytogenes infection and arthritis .
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Cat. No.: HY-162492
CAS No.: 3050773-93-5
Target:  

Influenza Virus

Research Areas:  

Infection

Influenza A virus-IN-14 (Compound 37) is an inhibitor for influenza virus type A (IAV), which inhibits H1N1 with an EC50 of 23 nM. Influenza A virus-IN-14 exhibits low cytotoxicity with CC50 of more than 100 μM. Influenza A virus-IN-14 inhibits cytopathic effect and improves the survival rates of cell Calu3. Influenza A virus-IN-14 exhibits synergistic activity with the neuraminidase inhibitor Oseltamivir (HY-13317). Influenza A virus-IN-14 exhibits poor pharmacokinetic properties in CD-1 mouse .
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Cat. No.: HY-170832
Research Areas:  

Cancer

Menin–KMT2A-IN-1 (Compound 20) is the inhibitor for menin–KMT2A that binds to menin with an IC50 of 8 nM, and inhibits the interaction between menin and lysine methyltransferase 2A (KMT2A). Menin–KMT2A-IN-1 inhibits hERG with an IC50 of 65 μM. Menin–KMT2A-IN-1 inhibits cell MV4-11 with an IC50 of 74 nM. Menin–KMT2A-IN-1 exhibits good pharmacokinetic characteristics in CD-1 mouse with an orally bioavailability of 74% .
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Cat. No.: HY-P5813
Synonyms: β-TRTX-CD1a; β-Theraphotoxin-CD1a
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Cd1a is a β-toxin derived from the African spider Ceratogyrus darlingi. Cd1a can regulate calcium ion channels. Cd1a inhibits human calcium ion channels (Cav2.2)(IC502.6 μM) and mouse sodium ion channels (Nav1.7). Cd1a can be used in the development of peripheral pain treatment drugs .
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Cat. No.: HY-P990869

Research Areas:  

Inflammation/Immunology Cancer

Anti-CD1a Antibody (OKT-6) is an anti-human CD1a IgG1 monoclonal antibody. Anti-CD1a Antibody (OKT-6) blocks T cell activation by blocking CD1a function. Anti-CD1a Antibody (OKT-6) can reduce the production of IFN-γ. Anti-CD1a Antibody (OKT-6) can be used for researches on cancer and inflammation such as leukemia. The recommend isotype control of Anti-CD1a Antibody (OKT-6): Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-P991846

Target:  

CD1

Research Areas:  

Inflammation/Immunology

Anti-CD1d Antibody (D5) reacts with the human CD1d. CD1d belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .
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Cat. No.: HY-P992059

Target:  

CD1

Research Areas:  

Cancer

Anti-Mouse CD1d Antibody (1B1) is an antibody targeting mouse CD1d (Kd=12.5 nM). By inserting into the lipid-binding groove of CD1d, Anti-Mouse CD1d Antibody (1B1) overlaps with the binding sites of type I and type II NKT cell receptors (TCR), thereby effectively blocking TCR-mediated interactions. Anti-Mouse CD1d Antibody (1B1) activates antigen-presenting cells such as dendritic cells and macrophages, induces them to release IL-12p70, and increases the levels of key cytokines including IL-12, IFN-γ and IFN-α in mouse serum. Anti-Mouse CD1d Antibody (1B1) can be used in studies related to renal cancer, breast cancer and colon adenocarcinoma. When combined with anti-DR5 or anti-CD137 antibodies and chemotherapeutic drugs, Anti-Mouse CD1d Antibody (1B1) exhibits significant tumor inhibitory and even eradication effects in mice .
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Cat. No.: HY-P7781
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NECTIN2; Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B); Prev. PVRL2; Herpes Virus Entry Mediator B; Prev. HVEB; Herpesvirus Entry Mediator B; Nectin-2; Herpesvirus Entry Protein B; PRR2; Poliovirus Receptor-Like 2; PVRR2; CD112 Antigen; CD1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P991890

Target:  

CD1

Research Areas:  

Others

Anti-CD1a Antibody is an antibody against human CD1a. Recommend Isotype Controls:?Mouse IgG1 kappa, Isotype Control (HY-P99977).
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Cat. No.: HY-P75437
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD1.1; CD1d1; CD1d.1; Antigen-presenting glycoprotein CD1d1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P75436
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CD1.1; CD1d1; CD1d.1; Antigen-presenting glycoprotein CD1d1
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76778
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD1.1; CD1d1; CD1d.1; Antigen-presenting glycoprotein CD1d1; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nk
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76779
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Antigen-presenting glycoprotein CD1d2; CD1d.2; CD1d2; CD1.2; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nk
Species:  
Mouse
Source:  
HEK293
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