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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
CD1d
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "CD1d" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: α-GalCer; KRN7000
Research Areas:
α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) [1] .
Cat. No.: HY-P990273
Cat. No.: HY-P990287
Target:
Research Areas:
Cat. No.: HY-144012A
CAS No.: 474922-84-4
Synonyms: 16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
Target:
Research Areas:
DPPE-PEG350 (16:0 PEG350 PE) is a CD1d lipid antagonist. DPPE-PEG350 blocks alpha-GalCer-dependent ERK tyrosine kinase phosphorylation in cells. DPPE-PEG350 inhibits cellular IL-4 and IFN-gamma production following alpha-GalCer stimulation. DPPE-PEG350 selectively antagonizes iNKT without affecting MHC class II-dependent OVA-specific Th2 responses. DPPE-PEG350 reduces MCP-1 and VCAM-1 protein expression and necrotic core formation in atherosclerotic lesions. DPPE-PEG350 can be used for research on asthma and atherosclerosis [1] .
Cat. No.: HY-RS02202
Target:
Research Areas:
CD1D Human Pre-designed siRNA Set A contains three designed siRNAs for CD1D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990807
Target:
Research Areas:
Cat. No.: HY-P992059
Cat. No.: HY-175365
Target:
Research Areas:
GCS-12–6 is a potent Th2-selective NKT cell agonist targeting CD1d protein. GCS-12–6 is promising for research of autoimmune diseases (e.g., inflammatory bowel disease, multiple sclerosis) [1].
Cat. No.: HY-P74326
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD1d; HMC Class I Antigen-Like Glycoprotein CD1d; CD1d Molecule; T-Cell Surface Glycoprotein CD1d; Antigen-Presenting Glycoprotein CD1d; Thymocyte Antigen CD1d; CD1d Antigen, D Polypeptide; CD1d; CD1d Antigen; R3; R3G1; B2M; Beta 2-Microglobulin; Beta-2-M
Species:
Human
Source:
HEK293
Cat. No.: HY-P74327A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD1d; HMC Class I Antigen-Like Glycoprotein CD1d; CD1d Molecule; T-Cell Surface Glycoprotein CD1d; Antigen-Presenting Glycoprotein CD1d; Thymocyte Antigen CD1d; CD1d Antigen, D Polypeptide; CD1d; CD1d Antigen; R3; R3G1
Species:
Human
Source:
E. coli
Cat. No.: HY-P705298
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD1d; HMC Class I Antigen-Like Glycoprotein CD1d; CD1d Molecule; T-Cell Surface Glycoprotein CD1d; Antigen-Presenting Glycoprotein CD1d; Thymocyte Antigen CD1d; CD1d Antigen, D Polypeptide; CD1d; CD1d Antigen; R3; R3G1; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1d4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:
Human
Source:
HEK293
Cat. No.: HY-P991846
Target:
Research Areas:
Cat. No.: HY-P991891
Cat. No.: HY-162727
Target:
Research Areas:
GCS-12 is a Th1/2-balanced sulfonamide glycolipid with improved interaction with CD1d. GCS-12 is an agonist for natural killer T (NKT) cell, that induces the secretion of cytokine IFN-γ and IL-4, and exhibits immunomodulatory and anti-tumor activities in mice [1].
Cat. No.: HY-171942A
Synonyms: C24:1-GM2 ammonium
Target:
Research Areas:
C24:1 Ganglioside GM2 (d18:1/24:1) (ammonium) is an endogenous monosialylated ganglioside. C24:1 Ganglioside GM2 (d18:1/24:1) (ammonium) is a self-lipid that can bind to CD1d in HEK293T cells [1] .
Cat. No.: HY-189458
Research Areas:
GCC-1 is a glycolipid. GCC-1 binds to CD1d to form a glycolipid-CD1d complex, which is presented to cellular TCR, thereby activating cells in a CD1d-dependent manner. GCC-1 induces Th1-biased cellular activation and IFN-γ production. GCC-1 can be used for research on colon adenocarcinoma [1].
Cat. No.: HY-181739
GCB-27a is a CD1d-binding immunostimulant and antitumor agent. GCB-27a binds to CD1d to form a stable complex and presents it to NKT cells, enhancing hydrophobic interactions within the A' pocket of CD1d through branched-chain conformation restriction. GCB-27a induces a Th1-biased immune response, drives IFN?γ production and limits IL-4 levels. GCB-27a is applicable to research related to melanoma lung metastasis [1].
Cat. No.: HY-102022R
CAS No.: 158021-47-7
Synonyms: α-GalCer (Standard); KRN7000 (Standard)
Research Areas:
α-Galactosylceramide (Standard) is the analytical standard of α-Galactosylceramide (HY-102022). This product is intended for research and analytical applications. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) [1] .
Cat. No.: HY-181740
GCB-27b is an immunostimulant that binds to CD1d. GCB-27b forms a stable and long-lasting complex with CD1d, which is presented to the TCR of NKT cells to drive immune responses. GCB-27b induces a Th1-skewed immune response in *Mus musculus*, resulting in high expression of IFN?γ with restricted IL-4 levels. GCB-27b is applicable to research related to lung metastasis of melanoma [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
