39 Results for "

CD40 ligand

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "CD40 ligand" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P72907
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P72908
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Mouse
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P7144
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P990083
CAS No.: 2628092-47-5
Synonyms: AT-1501

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Tegoprubart (AT-1501) is a CD40 ligand inhibitor (EC50=100 ng/mL) and immunosuppressant that selectively inhibits the CD40 ligand, a co-stimulatory molecule involved in T cell activation. Tegoprubart suppresses immune rejection, prevents rejection in animal transplantation models, and reduces cell-mediated and antibody-mediated immune responses to create a more immunotolerant environment. Tegoprubart preserves renal function when combined with Mycophenolate (HY-B0421) and Corticosteroids, and maintains graft function in preclinical studies. Tegoprubart is applicable to research related to kidney transplantation and kidney transplant rejection .
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Cat. No.: HY-P99625
CAS No.: 2515463-86-0
Synonyms: SAR441344; INX-021

Target:  

TNF Receptor

Frexalimab (SAR441344) is a second-generation monoclonal antibody targeting the CD40 ligand (CD40L) with a good safety profile. Frexalimab inhibits the binding between CD40 and CD40L to modulate immune response. Frexalimab is likely to help prevent the process of β-cell destruction. Frexalimab is proming for multiple sclerosis, lupus erythematosus, Sj gren’s syndrome and type I diabetes research .
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Cat. No.: HY-P99845
CAS No.: 2245953-10-8
Synonyms: MEDI-4920; VIB 4920
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Dazodalibep (MEDI-4920) is a non-antibody fusion protein that acts as a CD40 ligand (CD40L) antagonist. Dazodalibep is used in the research of rheumatoid arthritis and Sj?gren's syndrome .
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Cat. No.: HY-P99325
CAS No.: 252662-47-8
Synonyms: IDEC-131; Anti-Human CD40 ligand Recombinant Antibody

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Toralizumab (IDEC-131) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab is an immunosuppressive agent. Toralizumab can lead to increased thrombosis. Toralizumab can be studied in research for diseases such as multiple sclerosis, systemic lupus erythematosus (SLE), and Crohn’s disease .
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Cat. No.: HY-P99257
CAS No.: 1453067-91-8
Synonyms: ASKP 1240

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Bleselumab (ASKP 1240) is a human anti-CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity (Kd: 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection .
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Cat. No.: HY-P991557

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

ABI793 is a human IgG1 anti-human CD154 (CD40 ligand) monoclonal antibody. ABI793 inhibits immune response by blocking the CD154-CD40 (IC50 = 75 nM) signaling pathway. ABI793 effectively prevents kidney transplant rejection. ABI793 can be used for research on immunological rejection .
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Cat. No.: HY-174737
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CD40LG mRNA encodes the human CD40 ligand (CD40LG) protein, a protein that is expressed on the surface of T cells. CD40LG regulates B cell function by engaging CD40 on the B cell surface.
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Cat. No.: HY-P705466
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; TRAP; Tumor necrosis factor ligand superfa; CD40 ligand; CD154; CD40lg; CD40l; Tnfsf5
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P72122
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Rabbit
Source:  
E. coli
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Cat. No.: HY-P72121
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Rhesus Macaque
Source:  
E. coli
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Cat. No.: HY-P70609
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumor Necrosis Factor (ligand) Superfamily, Member 5 (Hyper-IgM Syndrome); TNF-Related Activation Protein; Hyper-IgM Syndrome; HCD40L; CD154 Antigen; CD154; IGM; CD40 ligand; Gp39
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78271
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumor Necrosis Factor (ligand) Superfamily, Member 5 (Hyper-IgM Syndrome); TNF-Related Activation Protein; Hyper-IgM Syndrome; HCD40L; CD154 Antigen; CD154; IGM; CD40 ligand; Gp39
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78425
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumor Necrosis Factor (ligand) Superfamily, Member 5 (Hyper-IgM Syndrome); TNF-Related Activation Protein; Hyper-IgM Syndrome; HCD40L; CD154 Antigen; CD154; IGM; CD40 ligand; Gp39
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P990083A
CAS No.: 2628092-47-5
Synonyms: AT-1501 (powder)

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Tegoprubart (powder) (AT-1501 (powder)) is a CD40 ligand inhibitor (EC50=100 ng/mL) and immunosuppressant that selectively inhibits the CD40 ligand, a co-stimulatory molecule involved in T cell activation. Tegoprubart (powder) suppresses immune rejection, prevents rejection in animal transplantation models, and reduces cell-mediated and antibody-mediated immune responses to create a more immunotolerant environment. Tegoprubart (powder) preserves renal function when combined with Mycophenolate (HY-B0421) and Corticosteroids, and maintains graft function in preclinical studies. Tegoprubart (powder) is applicable to research related to kidney transplantation and kidney transplant rejection .
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Cat. No.: HY-P72907AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P78934
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P71910
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:  
Human
Source:  
E. coli
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