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85 Results for "

CK2 Inhibitor

" in MedChemExpress (MCE) Product Catalog:

Products (85)

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1253

LY294002

1253 Publications Verification

Cat. No.: HY-10108

CAS No.: 154447-36-6

Purity: 99.86%

Target:

PI3K Casein Kinase DNA-PK Apoptosis Autophagy

Research Areas:

Infection Cancer

LY294002 is a broad-spectrum inhibitor of PI3K with IC₅₀s of 0.5, 0.57, and 0.97 μM for PI3Kα, PI3Kδ and PI3Kβ, respectively . LY294002 also inhibits CK2 with an IC₅₀ of 98 nM . LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC₅₀ of 1.4 μM. LY294002 is an apoptosis activator .

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1253

LY294002 hydrochloride

1253 Publications Verification

Cat. No.: HY-10108A

CAS No.: 934389-88-5

Purity: 99.93%

Target:

PI3K Casein Kinase DNA-PK Apoptosis

Research Areas:

Cancer

LY294002 hydrochloride is a potent and broad-spectrum PI3K inhibitor, with IC₅₀ values of 0.5, 0.57, and 0.97 μM for P110α, P110δ and P110β, respectively. LY294002 hydrochloride also inhibits CK2 with an IC₅₀ of 98 nM. LY294002 hydrochloride can be used for pancreatic cancer research .

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Silmitasertib

61 Cited Publications

Cat. No.: HY-50855

CAS No.: 1009820-21-6

Synonyms: CX-4945

Target:

Casein Kinase Autophagy

Research Areas:

Cancer

Silmitasertib (CX-4945) is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC₅₀ values of 1 nM against CK2α and CK2α'.

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Silmitasertib sodium salt

61 Cited Publications

Cat. No.: HY-50855B

CAS No.: 1309357-15-0

Synonyms: CX-4945 sodium salt

Target:

Casein Kinase Autophagy

Research Areas:

Cancer

Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC₅₀ values of 1 nM against CK2α and CK2α'.

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