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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
133 Results for "
CRF
" in MedChemExpress (MCE) Product Catalog:
Products (133)
133 Results for "CRF" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: NBI30775
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R121919 (NBI30775) is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats .
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Antisauvagine-30 (aSvg-30) is a selective peptide antagonist of the CRF2 receptor, with an IC50 of 1.1 nM for mouse CRF2. Antisauvagine-30 modulates cAMP signaling, gastric emptying, food intake, fear conditioning, anxiety-like behavior, stress responses, corticosterone levels, c-Fos expression, and CRF expression. Antisauvagine-30 is used in studies of anxiety-related disorders .
5
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Antisauvagine-30 TFA (aSvg-30 TFA) is a selective peptide antagonist of the CRF2 receptor, with an IC50 of 1.1 nM for mouse CRF2. Antisauvagine-30 TFA modulates cAMP signaling, gastric emptying, food intake, fear conditioning, anxiety-like behavior, stress responses, corticosterone levels, c-Fos expression, and CRF expression. Antisauvagine-30 TFA is used in studies of anxiety-related disorders .
3
3 Cited Publications
Cat. No.: HY-P0086
CAS No.: 86784-80-7
Synonyms: Human CRF; Human corticotropin-releasing factor
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3
3 Cited Publications
Cat. No.: HY-P0257
CAS No.: 170809-51-5
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3
3 Cited Publications
Cat. No.: HY-P2287
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2
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1
1 Cited Publications
Cat. No.: HY-P2847
CAS No.: 330648-32-3
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1
1 Cited Publications
Cat. No.: HY-P1294
CAS No.: 90880-23-2
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1
1 Cited Publications
Cat. No.: HY-P1858A
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1
1 Cited Publications
Cat. No.: HY-P1858
CAS No.: 357952-10-4
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1
1 Cited Publications
Cat. No.: HY-P1294A
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1
1 Cited Publications
Cat. No.: HY-P1368
Synonyms: Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)
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1
1 Cited Publications
Cat. No.: HY-P1297
CAS No.: 120066-38-8
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1
1 Cited Publications
Cat. No.: HY-P1368A
Synonyms: Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41) TFA
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1
1 Cited Publications
Cat. No.: HY-P72599
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10RB; CDW210B; Prev. D21S58; IL-10 Receptor Subunit Beta; Prev. D21S66; IL-10R Subunit Beta; Prev. CRFB4; IL-10R Subunit 2; IL-10R2; IL-10RB; CRF2-4; Cytokine Receptor Family II, Member 4; Interleukin-10 Receptor Subunit Beta; Cytokine Receptor Class-II
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77969
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL22RA1; Interleukin 22 Receptor, Alpha 1; Prev. IL22R; IL-22R-Alpha-1; CRF2-9; IL-22RA1; Interleukin-22 Receptor Subunit Alpha-1; ZcytoR11; Cytokine Receptor Class-II Member 9; Interleukin 22 Receptor; Cytokine Receptor Family 2 Member 9; IL22R1; Interle
Species:
Mouse
Source:
HEK293
Cat. No.: HY-106203
CAS No.: 752253-39-7
Synonyms: SSR-125543
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Crinecerfont (SSR-125543) is an orally effective corticotropin-releasing factor receptor type-1 (CRF1 receptor) antagonist. Crinecerfont blocks CRF1 receptor signaling to reduce adrenocorticotropic hormone secretion. Crinecerfont improves hypothalamic-pituitary-adrenal axis negative feedback sensitivity in chronically stressed mice. Crinecerfont can be used for the research of chronic stress conditions and classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency . Crinecerfont is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-P1295
CAS No.: 176591-49-4
Synonyms: Urocortin (human); Human urocortin; Human urocortin 1; Human urocortin I
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Synonyms: GSK561679
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Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
