48 Results for "

CT-26

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "CT-26" in MCE Product Catalog:

4
PD-1/PD-L1-IN-9
PD-1/PD-L1-IN-9
0 Images
4 Cited Publications
Cat. No.: HY-132192
CAS No.: 2628506-54-5
Purity:  99.59%
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model .
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4
PD-1/PD-L1-IN-9 hydrochloride
PD-1/PD-L1-IN-9 hydrochloride
0 Images
4 Cited Publications
Cat. No.: HY-132192A
Purity:  99.26%
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-1/PD-L1-IN-9 hydrochloride is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 hydrochloride can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 hydrochloride also exhibits significant in vivo antitumor activity in a CT26 mouse model .
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3
Fendiline hydrochloride
Fendiline hydrochloride
0 Images
3 Cited Publications
Cat. No.: HY-B0984
CAS No.: 13636-18-5
Target:  

Calcium Channel Ras STING Autophagy

Research Areas:  

Infection Cardiovascular Disease Cancer

Fendiline hydrochloride, a diphenylalkylamine type of antianginal agent, is an L-type calcium channel blocker (IC50 of 17 µM). Fendiline hydrochloride is also a selective K-Ras inhibitor, and has no effect on H-Ras and N-Ras. Fendiline hydrochloride inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM), inhibits K-Ras signal output and blocks the proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras. Fendiline hydrochloride is a STING agonist and is able to inhibit the growth of multiple refractory cold tumors (MC38, CT26 and B16F10) .
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3
Fendiline
Fendiline
0 Images
3 Cited Publications
Cat. No.: HY-B0984A
CAS No.: 13042-18-7
Target:  

Calcium Channel Ras STING Autophagy

Research Areas:  

Infection Cardiovascular Disease Cancer

Fendiline, a diphenylalkylamine type of antianginal agent, is an L-type calcium channel blocker (IC50 of 17 µM). Fendiline is also a selective K-Ras inhibitor, and has no effect on H-Ras and N-Ras. Fendiline inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM), inhibits K-Ras signal output and blocks the proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras. Fendiline is a STING agonist and is able to inhibit the growth of multiple refractory cold tumors (MC38, CT26 and B16F10) .
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2
Licoisoflavone A
Licoisoflavone A
0 Images
2 Cited Publications
Cat. No.: HY-N3389
CAS No.: 66056-19-7
Category:  

Flavonoids Metabolic Disease Phenols Polyphenols 500 - Internal Server Error | MedChemExpress

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