1 Result for "

CVI-LM001

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CVI-LM001" in MCE Product Catalog:

Cat. No.: HY-148626
CAS No.: 1233353-74-6
Target:  

PCSK9 AMPK LDLR

CVI-LM001 is an orally active PCSK9 inhibitor. CVI-LM001 inhibits PCSK9 transcription and suppresses PCSK9 mRNA expression, reducing circulating PCSK9. CVI-LM001 stabilizes LDLR mRNA and increases hepatic LDLR expression. CVI-LM001 induces hepatic AMPK phosphorylation, alleviates hepatic steatosis, reduces triglyceride synthesis, promotes fatty acid oxidation, and lowers serum and hepatic lipid levels. CVI-LM001 can be used for research on hypercholesterolemia and metabolic dysfunction-associated steatotic liver disease .
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