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88 Results for "

CYP51

" in MedChemExpress (MCE) Product Catalog:

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Tebuconazole

4 Cited Publications

Cat. No.: HY-B0852

CAS No.: 107534-96-3

Target:

Environmental Pollutants Apoptosis Cytochrome P450 Fungal

Research Areas:

Infection

Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC₅₀s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells .

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August 31

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Oteseconazole

2 Cited Publications

Cat. No.: HY-17643

CAS No.: 1340593-59-0

Synonyms: VT-1161

Target:

Fungal Cytochrome P450

Research Areas:

Infection

Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (K_d ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .

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